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Shingles Vaccine

All articles tagged with #shingles vaccine

medical-research13 hours ago•12 min saved

US switch to recombinant shingles vaccine linked to lower cardiovascular risk

A Nature Medicine study using US electronic health record data finds that older adults vaccinated predominantly with the recombinant shingles vaccine exhibit a lower cardiovascular disease burden over seven years, with reduced risks for heart failure and ischemic heart disease, and a modest, sex-specific reduction in ischemic stroke; though associations persist across analyses, causality cannot be established and effects may wane over time.

via News-Medical|

#cardiovascular-disease #medical-research #nature-medicine

health1 day ago•6 min saved

Shingrix linked to lower dementia risk in older adults, study suggests

A Brown University study of more than 509,000 adults aged 66+ found that those who had at least one Shingrix dose showed a 24% relative reduction in dementia diagnoses over four years versus unvaccinated peers, based on electronic health records and Medicare data; researchers stress this is an association, not proof of causation, and the vaccine’s primary purpose is shingles prevention, though explanations include fewer shingles-related complications and potential vascular benefits. The study was funded by GSK.

via Fox News|

#dementia-risk #health #observational-study

health1 day ago•46 min saved

Shingles vaccine may be linked to reduced dementia risk, neurologist says

Neurologist Dr. Ajeet Sodhi explains that while some research links the shingles vaccine to a lower dementia risk, the findings show an association rather than proof of causation, and more studies are needed to establish any definitive protective effect.

via Yahoo|

#ajeet-sodhi #dementia-risk #health

science1 day ago•22 min saved

Shingrix Could Protect the Heart for Years, Study Suggests

A US study of about 70,000 adults aged 60+ found that the recombinant shingles vaccine Shingrix is associated with a lower risk of cardiovascular disease years after vaccination compared with the older live vaccine, with the strongest effect on ischemic heart disease and heart failure; the finding hints at immune-system changes beyond shingles, though the observational design aims to reduce bias by comparing groups who chose vaccination rather than vaccinated versus unvaccinated.

via ZME Science|

#cardiovascular-disease #immune-system #observational-study

health-and-medicine3 days ago•6 min saved

Shingrix May Cut Dementia Risk by Nearly a Quarter in Seniors

A Brown University–led analysis of more than 500,000 adults aged 66+ in skilled nursing facilities found that receiving at least one Shingrix dose was associated with a 24% lower risk of a dementia diagnosis over four years, compared with unvaccinated peers (18.8% vs 24.6%). Using Medicare claims and electronic health records with target trial emulation, the study cannot prove causation and may reflect healthier baseline status among vaccine recipients; more research, including trials, is needed. Funding from GlaxoSmithKline was disclosed, though the sponsor had no control over study design or publication.

via Science Daily|

#aging #dementia-risk #health-and-medicine

health4 days ago•14 min saved

Vaccines May Slow Dementia: A Welsh Natural Experiment Sparks New Hope

A 2013 Welsh, age-based shingles-vaccine rollout created a natural experiment showing people offered the vaccine were about 20% less likely to develop dementia, with some data suggesting vaccines might also slow progression in those already with dementia. Across multiple vaccines (influenza, BCG, shingles, and others) there are growing links to lower dementia risk, likely via trained immunity that broadens immune protection. While promising, dementia vaccines face past trial failures and require coordinated, long-term research and funding before they can become a widespread preventive strategy.

via BBC Science Focus Magazine|

#dementia #health #immunotherapy

pharma1 month ago•3 min saved

GSK kicks off large trial to test shingles vaccine for dementia prevention

GSK is launching a large study to determine whether the shingles vaccine Shingrix can lower dementia risk, prompted by observational data suggesting vaccinated individuals may have fewer dementia cases; the trial aims to establish causality and could influence dementia prevention strategies if results are favorable.

via Endpoints News|

#alzheimers-disease #dementia-prevention #gsk

health2 months ago•53 min saved

Four simple steps to add healthy years

A Vox-tied look at longevity highlights a potential dementia-reducing link from the shingles vaccine, but the practical core emphasizes four actions: stay socially connected to cut isolation-related risk, follow a Mediterranean-style diet for cancer/heart/cognitive benefits, engage in regular strength training to preserve muscle, and prioritize sleep—especially deep sleep—with a consistent schedule. The goal is to maximize healthy years (healthspan) rather than chasing an arbitrary longevity number, and it’s never too late to start.

via Yahoo|

#health #healthspan #longevity

health2 months ago•4 min saved

Diet, vaccine, and drug linked to lower stroke risk in new studies

Three new studies suggest potential stroke-prevention strategies: a Mediterranean-style diet may lower risk of ischemic and hemorrhagic stroke in women; the shingles vaccine was associated with fewer major adverse cardiac events in people with ASCVD in an observational study (not yet peer-reviewed, so causality isn’t established); and the oral anticoagulant asundexian may reduce secondary ischemic stroke risk in patients who’ve had a prior stroke or high‑risk TIA by inhibiting factor XIa. Stroke is a leading cause of death, with many events potentially preventable through lifestyle and medical interventions.

via Medical News Today|

#asundexian #health #mediterranean-diet

health2 months ago•7 min saved

Shingrix Vaccine Linked to Lower Dementia Risk in Nursing Home Residents

A Brown University-led analysis of more than 500,000 Medicare beneficiaries found that older adults who received the Shingrix shingles vaccine after entering skilled nursing facilities had about 24% fewer dementia diagnoses over four years compared with those unvaccinated, though the study cannot prove causation and residual differences between groups may influence results.

via SciTechDaily|

#dementia #elderly #gerontology

health2 months ago•5 min saved

Shingrix May Cut Dementia Risk by 24% in Seniors, Study Finds

A real-world study of 509,926 nursing‑facility residents found that those who received the Shingrix shingles vaccine within 12 months of admission had a 24% lower risk of developing dementia over four years than unvaccinated peers, though the observational design cannot establish causation. Uptake was low (8,843 vaccinated), and researchers note potential neuroinflammatory mechanisms and confounders; the study was funded by GlaxoSmithKline, and Shingrix’s real‑world cognitive benefits add to questions about why vaccines might protect brain health.

via ScienceAlert|

#dementia #elderly #health

health3 months ago•4 min saved

Shingrix May Cut Dementia Risk in Older Americans, Large Study Finds

A large U.S. Medicare study (1.5 million beneficiaries) found that older adults who received the two-dose recombinant zoster vaccine (Shingrix) had a lower incidence of dementia than unvaccinated peers, with about a 28–33% reduced risk for any dementia, Alzheimer's disease, and vascular dementia over up to three years and continued protection beyond three years; results are observational and can’t prove causality, but align with other real-world evidence and call for trials to confirm.

via MedPage Today|

#alzheimers-disease #dementia #health

health3 months ago•3 min saved

FDA Pulls Vaccine Safety Publications Over Data-Driven Discrepancies

FDA withdrew the publication of safety studies on COVID-19 and shingles vaccines after authors drew broad conclusions not supported by the underlying data, a move the agency says preserves scientific integrity; the piece also notes vaccine-policy shifts tied to RFK Jr.’s stance, while health officials reiterate that vaccines remain safe and effective.

via ABC News - Breaking News, Latest News and Videos|

#covid-19 #fda #health

health5 months ago•5 min saved

Shingles vaccine linked to fewer heart complications in people with heart disease

A large observational study of more than 246,000 U.S. adults with established atherosclerotic cardiovascular disease found that receiving at least one shingles vaccine dose (Shingrix or Zostavax) was associated with substantially lower risks of major cardiovascular events within a year, including a 46% drop in major adverse cardiovascular events, 27% fewer heart attacks, 27% fewer strokes, 33% fewer heart failures, and a 61% reduction in death from any cause, compared with unvaccinated peers. The researchers caution that causality cannot be proven from observational data and longer follow-up is needed, but the findings add to evidence that the shingles vaccine may offer broader health benefits and support vaccination guidelines for adults 50 and older, especially those with cardiovascular disease.

via Medical News Today|

#cardiovascular-disease #health #heart-attack

health5 months ago•23 min saved

Market-Ready Meds Could Slow Dementia, Panel Finds

An international expert panel identifies eight drugs already on the market as candidates for further study to prevent or slow dementia. The shingles vaccine shows the strongest real‑world signal, with Welsh data suggesting about a 20% reduction in dementia risk among recipients; the newer Shingrix vaccine is anticipated to be at least as effective. Other drugs cited include Viagra (sildenafil), riluzole, Gilenya (fingolimod), and vortioxetine, though evidence for these is less clear and confounded by factors such as lifestyle and relationships. The panel emphasizes more rigorous research and potential trials to determine true benefits at the population level.

via MarketWatch|

#alzheimers #dementia #health