Metabolism-boosting compound may spark fat burn without dulling appetite

TL;DR Summary
In a mouse study, TOFA increased energy expenditure by about 18% and promoted weight loss by boosting metabolism without reducing lean muscle or appetite; it blocks liver fat production, lowers triglycerides, and improves insulin sensitivity and fatty liver markers. When used with GLP-1 drugs, TOFA showed greater improvements across weight, glucose control, and lipids, though human safety and efficacy remain untested.
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