Small DMT Trial Signals Potential Depression Treatment
TL;DR
A small UK Phase IIa randomized, placebo-controlled trial found that a single dose of DMT with psychotherapy significantly reduced depressive symptoms for up to three months (some participants up to six); 47% reached remission at three months. DMT appeared safe and well tolerated, but the study's small size means larger, longer trials are needed before it could become a standard depression treatment.
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- Single dose of potent psychedelic drug could help treat depression, trial shows The Guardian
- Nature Medicine Publishes Helus Pharma’s Randomized, Placebo-Controlled Phase 2a Trial of SPL026 in Major Depressive Disorder Yahoo Finance
- Psychedelic found in Amazonian brew ayahuasca shows anti-depression promise Financial Times
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