Psilocybin May Shield Nerves From Chemotherapy, Mouse Study Suggests
TL;DR Summary
A mouse study published in Science found that psilocybin, given before chemotherapy, can prevent chemotherapy-induced peripheral neuropathy by preserving mitochondrial trafficking and ATP production in nerve endings. The protective effect relies on the serotonin receptor 5-HT2A, and a non-hallucinogenic 5-HT2A activator also provided protection. Human trials have not yet proven efficacy, though researchers plan to move toward clinical testing.
- Psilocybin may protect against a common, debilitating side effect of chemotherapy, early study finds Live Science
- Psilocybin May Prevent Nerve Damage Caused by Chemotherapy, Study Finds The New York Times
- NEWSLETTER: Psychedelic drug shows promise for preventing chemotherapy-induced nerve damage Reuters
- Psilocybin could prevent common and debilitating chemotherapy side effect New Scientist
- Psilocybin prevents chemotherapy-related nerve injury and associated symptoms in preclinical models Medical Xpress
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