Tag

Peripheral Neuropathy

All articles tagged with #peripheral neuropathy

medicine-and-drugs1 month ago•111 min saved

Psilocybin May Shield Nerves From Chemotherapy, Mouse Study Suggests

A mouse study published in Science found that psilocybin, given before chemotherapy, can prevent chemotherapy-induced peripheral neuropathy by preserving mitochondrial trafficking and ATP production in nerve endings. The protective effect relies on the serotonin receptor 5-HT2A, and a non-hallucinogenic 5-HT2A activator also provided protection. Human trials have not yet proven efficacy, though researchers plan to move toward clinical testing.

via Live Science|

#5-ht2a #chemotherapy #medicine-and-drugs

health5 months ago•13 min saved

Ohio trial tests glove-and-boot device to curb chemo nerve damage

Mercy Health’s Springfield and Urbana Cancer Centers have begun the IMPACT clinical trial testing the Lilac Glove & Boot, a device that gently compresses the hands and feet during chemotherapy to potentially reduce chemotherapy‑induced peripheral neuropathy, a nerve‑damage side effect that can cause numbness, tingling, pain and impaired daily activities. Participants will use either the active device or a comparator and be closely monitored to help determine if this approach preserves function and quality of life for central Ohio cancer patients.

via Peak of Ohio|

#cancer #chemotherapy #clinical-trial

science6 months ago•10 min saved

Salk to Lead $41M ARPA-H Initiative to Make Ultrasound-Controlled Therapies a Reality

Salk Institute researcher Sreekanth Chalasani will lead a multi-institution ARPA-H program, funded up to $41.3 million over about 5.5 years, to advance sonogenetics—the use of ultrasound to control engineered cells—into a clinical therapy by building a protein toolkit, a wearable ultrasound delivery system, and preclinical data across partner sites toward trials, with potential applications such as peripheral neuropathies.

via Salk Institute for Biological Studies|

#arpa-h #peripheral-neuropathy #science

health1 year ago•3 min saved

Foot Symptoms May Indicate Common Diseases, Doctor Warns

Dr. Eric Berg highlights how foot symptoms can indicate broader health issues, such as numb feet signaling peripheral neuropathy or foot cramps suggesting magnesium deficiency. He advises consulting healthcare providers for any concerns. The NHS also recommends seeing a GP for symptoms like swollen feet, which may relate to diabetes, or discolored legs, possibly indicating deep vein thrombosis. Proper diagnosis and treatment are crucial for managing these conditions.

via Surrey Live|

#disease-symptoms #dr-eric-berg #foot-health

science-and-technology2 years ago•4 min saved

Unlocking the Potential of Adipose Tissue: A Breakthrough in Nerve Repair

Scientists at the Salk Institute have discovered that the protein Mitf plays a crucial role in repairing nerve damage in peripheral neuropathy. This breakthrough could lead to the development of innovative therapies that enhance nerve repair functions, potentially benefiting millions of people suffering from this condition. The researchers found that Mitf activates the repair function in specialized Schwann cells of the nervous system, offering a promising new therapeutic target for treating peripheral neuropathy.

via SciTechDaily|

#nerve-repair #peripheral-neuropathy #protein-mitf