Tag

Chemotherapy

All articles tagged with #chemotherapy

NAD+-Boosting Supplements May Help Pancreatic Cancer Survive Chemotherapy
health22 hours ago

NAD+-Boosting Supplements May Help Pancreatic Cancer Survive Chemotherapy

A Case Western Reserve University study suggests over-the-counter NAD+-boosting derivatives NMN, NR, and NAM may enable pancreatic cancer cells to withstand chemotherapy (oxaliplatin, 5-fluorouracil, gemcitabine) in lab and animal tests. While NAD+ boosts can benefit healthy cells, cancer cells may gain energy to repair chemo damage, prompting caution for patients undergoing treatment and routine screening of supplement use by oncology teams; findings are not yet proven in humans and more research is needed.

Three-year-old’s battle to save her sight with 14 months of chemo for NF1 brain tumors
health7 days ago

Three-year-old’s battle to save her sight with 14 months of chemo for NF1 brain tumors

A 3-year-old girl with neurofibromatosis type 1 developed two optic pathway gliomas that threatened her vision. After café-au-lait spots led to an NF1 diagnosis, brain MRIs revealed the tumors. Maddie Fries underwent 14 months of weekly chemotherapy beginning mid-2024, including chest-port placement for infusions, to stabilize the tumors and preserve her sight. Her vision remains impaired but stable (about 20/60 with glasses), and she continues regular MRIs and eye exams; she’s starting kindergarten this August, highlighting the lifelong vigilance NF1 requires.

OU study ties cholesterol use to pancreatic cancer resilience, tests statin combo therapy
medical-research-news17 days ago

OU study ties cholesterol use to pancreatic cancer resilience, tests statin combo therapy

University of Oklahoma researchers have received a five-year, $2 million NCI grant to study how pancreatic ductal adenocarcinoma reprograms cholesterol metabolism, guided by the RNA-binding protein ZC3H15, which helps cancer cells resist chemotherapy and undergo EMT. The team will use patient-derived models and mice to uncover cholesterol-driven survival mechanisms and will evaluate adding rosuvastatin to FOLFIRINOX to improve treatment effectiveness.

health19 days ago

Fructose as a Hidden Signal May Drive Ovarian Cancer Spread

Researchers at The Wistar Institute found that fructose released by treatment-surviving ovarian cancer cells acts as a signal that weakens cell–cell adhesion and promotes detachment and spread. The effect can occur even without chemotherapy, and higher dietary fructose may influence tumor behavior, with cholesterol-lowering statins also weakening cancer cell adhesion. The study, published in Nature Aging, raises the possibility that this mechanism could occur in other torso-spreading cancers, though clinical studies are needed.

Sweet Signal: Fructose Secreted by Chemo-Treated Cells May Drive Ovarian Cancer Spread
health-and-medicine21 days ago

Sweet Signal: Fructose Secreted by Chemo-Treated Cells May Drive Ovarian Cancer Spread

Researchers at The Wistar Institute report that fructose released by chemotherapy-surviving ovarian cancer cells acts as a signal to neighboring tumor cells, promoting detachment and metastatic spread. In preclinical tests, high dietary fructose could enhance cancer spread by lowering cholesterol production in nearby cells, weakening cell adhesion; the finding also suggests interactions with cholesterol-lowering drugs (statins). While intriguing, these effects have not been tested in patients, and researchers caution against changing medications yet. More studies are planned to see if this pathway affects other cancers and whether diet or statin use could influence outcomes.

Fructose may fuel cancer spread after chemotherapy, study suggests
science24 days ago

Fructose may fuel cancer spread after chemotherapy, study suggests

A new study finds the sugar fructose produced by chemotherapy-surviving tumor cells can signal neighboring cancer cells to spread, potentially affecting ovarian cancer progression and raising questions about diet and statin interactions. The findings are preclinical and suggest nutrition could influence cancer progression, but more research is needed before changing patient care.

Early Therapy Switching Could Foil Cancer Resistance, Researchers Say
science1 month ago

Early Therapy Switching Could Foil Cancer Resistance, Researchers Say

A new strategy proposes changing cancer therapies while tumors are still shrinking, using evolutionary modeling to prevent resistant cells from taking over. By not waiting for relapse, doctors could shorten the window for resistance to develop; three small clinical trials are underway, and models suggest that sequences of two or more therapies may outperform current practice, especially for larger tumors, though further lab and patient trials are needed to validate the approach.

RHOC alum Jeana Keough battles tongue cancer as family launches GoFundMe for treatment
entertainment1 month ago

RHOC alum Jeana Keough battles tongue cancer as family launches GoFundMe for treatment

Jeana Keough’s children provided an update on her tongue cancer diagnosis, saying she’s strong with a solid support network in California. After surgeries to remove the cancer and affected lymph nodes, doctors found it had spread and she is in the fifth week of a demanding treatment plan that includes chemotherapy, radiation, and immunotherapy, with significant pain and nutrition challenges. A GoFundMe fundraiser to cover treatment has surged from about $22,000 to roughly $90,000, with donations from fans and Bravo colleagues like Andy Cohen.

RHOC Alum Jeana Keough’s Cancer Battle Pauses as DVT and Infection Slows Treatments
entertainment1 month ago

RHOC Alum Jeana Keough’s Cancer Battle Pauses as DVT and Infection Slows Treatments

Real Housewives of Orange County alum Jeana Keough’s tongue cancer treatment has been paused after doctors found a deep vein thrombosis in her leg and an infection, delaying a feeding-tube procedure and forcing chemotherapy and radiation to pause temporarily; her daughter Kara posted updates and a GoFundMe campaign was launched to support her care as the family prays for quick clearance of the infection so she can resume treatment.

Jeana Keough Fights Tongue Cancer as Family Rallies Financial Support
entertainment1 month ago

Jeana Keough Fights Tongue Cancer as Family Rallies Financial Support

Former Real Housewives of Orange County star Jeana Keough, 70, has been diagnosed with tongue squamous cell carcinoma. After initial surgery, cancer spread to lymph nodes, and she is in the fifth week of a treatment regimen that includes chemotherapy, radiation, and immunotherapy. Her daughter launched a GoFundMe to cover medical and living expenses, aiming for $50,000; the fundraiser quickly surpassed $40,000. The family, along with supporters like Tamra Judge, emphasize that the treatments are exhausting and financially burdensome as Keough cannot work during this period.

From Shaved Head to Chemo Curls: A Survivor’s Hair Regrowth Story
lifestyle1 month ago

From Shaved Head to Chemo Curls: A Survivor’s Hair Regrowth Story

A UK breast cancer survivor, Chloe Williams, shared on Instagram how chemotherapy caused hair and eyelash loss but eventually led to regrowth with distinctive curls, documenting the journey from shaving her head to embracing her hair’s new texture and style, and offering hope to others; WHO data note 694,000 breast cancer deaths globally in 2024 and that it was the most common cancer in women in 164 of 186 countries.

Sam Neill’s Final Days Revealed: Ex Details Cancer Battle and Sudden Death
entertainment1 month ago

Sam Neill’s Final Days Revealed: Ex Details Cancer Battle and Sudden Death

Sam Neill’s ex Laura Tingle said the actor had been battling cancer for years, undergoing extensive chemotherapy and immunotherapy that left his immune system compromised. He died at 78 in Sydney in what his family described as a sudden, unexpected loss, noting he passed away with dignity and while cancer was reportedly no longer active; pneumonia was reported by some sources in the days leading up to his death.

Misdiagnosis Led to Years of Unnecessary Chemo for 12-Year-Old
health1 month ago

Misdiagnosis Led to Years of Unnecessary Chemo for 12-Year-Old

A British girl, Faye Condon, was misdiagnosed with Juvenile Dermatomyositis at age 5 and underwent six rounds of chemotherapy and home injections for seven years before doctors at Great Ormond Street Hospital correctly diagnosed de novo Emery-Dreifuss muscular dystrophy. The treatments had no effect, and she now faces progressive disability including wheelchair use and nocturnal ventilation. Her mother is filing a formal complaint against Bristol Children’s Hospital, blaming budget constraints and urging genetic testing to prevent future misdiagnoses.