Gene Editing Successfully Eliminates HIV-like Virus in Non-Human Primates, Offering Hope for a Cure

Scientists at the Lewis Katz School of Medicine at Temple University have successfully used a novel CRISPR gene-editing treatment to remove SIV, a virus related to HIV, from the genomes of non-human primates. The treatment, called EBT-001, effectively excised SIV from viral reservoirs without any detectable off-target effects. This breakthrough paves the way for the first-ever clinical trial of an HIV gene-editing technology in human patients. The treatment, EBT-101, has the potential to revolutionize HIV therapeutics and is currently being tested for safety and tolerability in clinical trials.