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Non Human Primates

All articles tagged with #non human primates

Gene Editing Successfully Eliminates HIV-like Virus in Non-Human Primates, Offering Hope for a Cure
science-and-technology3 years ago

Gene Editing Successfully Eliminates HIV-like Virus in Non-Human Primates, Offering Hope for a Cure

Scientists at the Lewis Katz School of Medicine at Temple University have successfully used a novel CRISPR gene-editing treatment to remove SIV, a virus related to HIV, from the genomes of non-human primates. The treatment, called EBT-001, effectively excised SIV from viral reservoirs without any detectable off-target effects. This breakthrough paves the way for the first-ever clinical trial of an HIV gene-editing technology in human patients. The treatment, EBT-101, has the potential to revolutionize HIV therapeutics and is currently being tested for safety and tolerability in clinical trials.

Advancements in HIV Cure Research: Gene Therapies and Stem Cells Show Promise.
health3 years ago

Advancements in HIV Cure Research: Gene Therapies and Stem Cells Show Promise.

Researchers from Oregon Health & Science University have discovered the mechanisms by which stem cell transplants can cure HIV, bringing us closer to a universal cure for AIDS. The study found that two non-human primates were cured of a form of HIV after stem cell transplantation, revealing that two factors must be present for a cure – the donor stem cells attacking the HIV-infected cells and preventing the virus from infecting the new cells. The findings provide valuable insights that can guide efforts to extend this curative strategy to a larger population.