Androgen loss may accelerate brain tumor growth through neuroinflammation
TL;DR Summary
A Nature News & Views piece summarizes Lee et al.'s finding that loss of male sex hormones triggers neuroinflammation and disrupts hormonal and immune signaling via the HPA axis, potentially accelerating brain tumor growth, contrasting with androgen-blockade benefits seen in many other cancers.
- Male sex hormone loss aids brain tumour growth Nature
- Androgen loss accelerates brain tumour growth via HPA axis activation Nature
- Testosterone suppresses brain tumor growth in males, study suggests Medical Xpress
- Glioblastoma: Testosterone Supplements Linked to 38% Lower Risk of Death Inside Precision Medicine
- NIH-Funded Research Indicates Testosterone May Inhibit Brain Tumor Growth in Males Bioengineer.org
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