Copper drug reboots brain cleanup pumps to cut Alzheimer's proteins in mice

1 min read
Source: ScienceAlert
Copper drug reboots brain cleanup pumps to cut Alzheimer's proteins in mice
Photo: ScienceAlert
TL;DR

A copper-containing drug Cu(ATSM) boosted brain P-glycoprotein pumps, increased clearance of amyloid-beta by about 42%, and improved spatial memory by about 44% over 56 days in Alzheimer's-model mice, suggesting a potential preclinical approach to restore brain waste clearance, though human trials and safety assessments remain essential.

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