Enzyme Destroys AGE Waste in Tissues, Showing Ex Vivo Rejuvenation Clues

TL;DR Summary
Scientists developed CMLase to break down N(6)-Carboxymethyllysine (CML), a damaging AGE that can impair tissue function. In ex vivo experiments, treating skin reduced CML by 55% and arterial tissue by 75%, suggesting AGE cleanup could improve tissue health, but safety and efficacy in living humans still need to be established through clinical trials.
- De-Aging Human Tissue Using Special Enzyme To Remove AGEs Hackaday
- Can This New Enzyme Turn Back the Clock in the Human Body? The New York Times
- New enzyme may reverse one cause of aging. Can we say goodbye to wrinkles forever? Miami Herald
- An enzyme might help fight against your body’s aging The Independent
- The Brutal Truth About Anti-Aging Enzymes and Biological Reversal Lavender Hotel
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