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ERBB4 receptor linked to early Alzheimer’s changes, offering a new therapeutic target

1 min read
Source: The Independent
ERBB4 receptor linked to early Alzheimer’s changes, offering a new therapeutic target
Photo: The Independent
TL;DR

A South Korean study suggests the ERBB4 receptor becomes abnormally active in excitatory neurons during Alzheimer's, triggering multiple disease processes. In mouse models, removing ERBB4 from these neurons reduced harmful brain activity, lessened glial reactivity and plaques, and improved memory, pointing to ERBB4 as an early driver of Alzheimer's pathology and a potential therapeutic target.

Topics:healthscience#alzheimers-disease#erbb4-receptor#neurodegenerative-disease#neurons#science#south-korea
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  1. Potential root cause of Alzheimer’s may have just been discovered  The Independent
  2. Scientists Find a Potential “Root” of Alzheimer’s Disease  SciTechDaily
  3. Researchers Think A Brain 'Switch' Could Be The Root Cause Of Alzheimer's  HuffPost UK
  4. Have scientists found the missing link between Alzheimer's nerve damage and memory loss?  bdnews24.com

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