Exercise Fuels a Brain-Protection Pathway That Fights Alzheimer’s (Mouse Study)
TL;DR
A UCSF study in mice shows exercise increases GPLD1 in the blood, which helps prune TNAP in brain blood vessels, strengthening the blood-brain barrier, reducing inflammation, and lowering amyloid beta clumps associated with Alzheimer's. The findings suggest a body-brain mechanism behind exercise’s cognitive benefits and point to potential therapies that mimic GPLD1, though human relevance remains to be confirmed.
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- Lifting weights may slow brain ageing: Neurologist newskarnataka.com
- Scientists find a mechanism for how exercise protects the brain Lake County News,California
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