Genetic Insights Offer New Hope for Autism Treatment and Brain Development
TL;DR
Researchers at Tel Aviv University have discovered that SHANK3 gene mutations, linked to autism, impair not only neurons but also oligodendrocytes, which are crucial for myelin production. This disruption reduces brain signal efficiency. Using gene therapy, they successfully repaired these cells in mice and human-derived stem cells, restoring their function and myelin production. This study highlights the significant role of oligodendrocytes in autism and suggests potential new treatments targeting myelin dysfunction.
- Gene Repair Restores Brain Signal Efficiency in Autism Neuroscience News
- Study reveals brain mechanisms involved in genetically based autism Medical Xpress
- Some genetic mutations may offer protection against developmental disorders MSN
- Protective genetic mutation offers new hope for understanding autism and brain development Medical Xpress
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