Intracellular Tug-of-War Between Amyloid Beta and Tau Redefines Alzheimer's Cause

UC Riverside researchers propose that Alzheimer’s disease may arise from a competition inside neurons where amyloid beta and tau vie for the same microtubule binding sites, disrupting intracellular transport; this could mean plaques are a downstream effect rather than the root cause and shift therapy toward preventing this intracellular interference or boosting protein clearance.