Largest GWAS uncovers first genetic risk clues for borderline personality disorder

A large, multi-study genome-wide association analysis of European- ancestry participants identified 11 genomic loci linked to borderline personality disorder, with nine nearby functional genes. Replication supported five additional loci, bringing the total to 11. The newly identified variants account for about 17% of inherited risk, indicating genetics play a meaningful but partial role in BPD.