Pesticide chlorpyrifos linked to nearly triple Parkinson's risk, UCLA study finds
TL;DR
A UCLA-led study links long-term chlorpyrifos exposure to about a 2.74-fold increase in Parkinson's disease risk, based on 829 PD cases and 824 controls using California pesticide-use data and residence/work addresses; animal models show dopamine neuron loss and alpha-synuclein buildup with autophagy disruption, which can be mitigated by stimulating autophagy, supporting a likely causal link while noting many factors influence PD and that chlorpyrifos use persists in the US.
Topics:healthscience#alpha-synuclein#autophagy#chlorpyrifos#parkinsons-disease#pesticide-exposure#science
- Common Pesticide Exposure Linked With 2.7x Risk of Parkinson's Disease ScienceAlert
- Widely Used Farm Chemical May More Than Double Parkinson’s Disease Risk SciTechDaily
- Long-term exposure to chlorpyrifos linked to Parkinson’s disease The New Lede
- Scientists warned about unexpected brain hazard from popular pesticide Baku.ws
- Pesticide exposure can double the risk of Parkinson’s disease AirQualityNews
Want the full story? Read the original reporting
Read on ScienceAlert