Sweeteners Leave Generational Footprints on Gut and Metabolism, Mouse Study Finds

A mouse study found that common zero-calorie sweeteners, sucralose and stevia, alter the gut microbiome and the activity of genes tied to metabolism and inflammation, with effects lingering into the second generation—more pronounced for sucralose. The research shows associations, not causation, and underscores the need for further human studies and moderation in consumption.