Tag

Artificial Sweeteners

All articles tagged with #artificial sweeteners

Xylitol in the blood linked to higher cardiovascular risk in large population study
health4 days ago

Xylitol in the blood linked to higher cardiovascular risk in large population study

An observational analysis using the CLSA and EPIC-Norfolk cohorts found that higher blood levels of xylitol are linked to a greater risk of major adverse cardiovascular events (heart attack, stroke, or death) in the general population, with a 57% higher risk over 6 years in CLSA and 18% higher over 30 years in EPIC-Norfolk, showing a dose-dependent pattern. The study does not establish causality and researchers urge further investigation, while experts advise moderating artificial sweeteners and favoring natural sweeteners when possible.

Everyday xylitol linked to higher cardiovascular risk in large study
health10 days ago

Everyday xylitol linked to higher cardiovascular risk in large study

An observational study of 17,710 participants from Canada and Europe found higher blood levels of the sweetener xylitol associated with a greater risk of major cardiovascular events, including heart attack and stroke. Canada showed a 57% higher risk over six years; Europe showed an 18% higher risk over 30 years, with risk rising as xylitol levels increased. The study cannot prove causation and researchers call for more studies, noting xylitol’s widespread use in gum, candies, toothpaste and other products.

Xylitol exposure tied to increased heart and stroke risk, study suggests
health11 days ago

Xylitol exposure tied to increased heart and stroke risk, study suggests

An ESC Congress presentation links high blood xylitol levels to a higher risk of major cardiovascular events, with a 57% higher risk over six years and 18% higher risk over 30 years in two cohorts after accounting for traditional risk factors; the study is observational and not yet peer‑reviewed, so causation isn’t proven and more research is needed as xylitol use grows.

Elevated blood xylitol linked to greater cardiovascular risk
health11 days ago

Elevated blood xylitol linked to greater cardiovascular risk

A large, long-term analysis of about 17,700 people found that higher blood levels of the artificial sweetener xylitol are associated with an increased risk of major cardiovascular events (death, heart attack, stroke) over six and 30 years, even after adjusting for traditional risk factors; findings suggest the cardiovascular safety of xylitol requires further study and will be presented at the ESC Congress 2026.

Higher xylitol blood levels linked to increased heart risk, study finds
health11 days ago

Higher xylitol blood levels linked to increased heart risk, study finds

An observational study presented at the ESC Congress found that higher blood xylitol levels are associated with a greater risk of major cardiovascular events (heart attack, stroke, or death) over six years (57% higher) and thirty years (18% higher) after adjusting for risk factors; the study does not prove causation and is not yet peer-reviewed, underscoring the need for further research as xylitol use in products grows.

Xylitol Blood Levels Linked to Higher Heart Risk, New Study Finds
health11 days ago

Xylitol Blood Levels Linked to Higher Heart Risk, New Study Finds

Two large cohorts found that higher blood levels of xylitol, a common sugar substitute, were associated with a greater risk of major cardiovascular events (death, heart attack, or stroke) over six to 30 years, with a dose‑dependent pattern that persisted after adjusting for age, sex, BMI, hypertension, diabetes and lipids. The study is observational and does not prove causation, and researchers say more work is needed as xylitol exposure in foods and products grows, amid calls for caution regarding artificial sweeteners.

Common sugar substitute xylitol tied to higher heart risk in two large cohorts
health12 days ago

Common sugar substitute xylitol tied to higher heart risk in two large cohorts

A large observational study of more than 17,700 Canadian and British participants links higher blood xylitol levels to a dose-dependent rise in major adverse cardiovascular events (death, heart attack, stroke), with a 57% higher risk in the Canadian cohort and 18% higher risk in EPIC-Norfolk; researchers caution that causality isn’t proven and more studies are needed.

Blood xylitol linked to higher cardiovascular risk in large study
health15 days ago

Blood xylitol linked to higher cardiovascular risk in large study

A large observational study presented at the European Society of Cardiology conference in Munich found that higher blood levels of xylitol are associated with a greater risk of major cardiovascular events (death, heart attack, or stroke) within six years, with lingering elevated risk over 30 years. The association appears dose‑dependent and persists after accounting for factors like age, sex, BMI, hypertension, diabetes and lipids. Researchers caution that causation cannot be established from observational data and call for further studies as xylitol usage in foods and oral care products continues to rise.

Xylitol Exposure Tied to Higher Heart-Risk Signals, Study Finds
health17 days ago

Xylitol Exposure Tied to Higher Heart-Risk Signals, Study Finds

A large observational analysis of about 17,000 participants from two long-running studies found that higher xylitol consumption correlates with a greater risk of major cardiovascular events (heart attack, stroke, death) over several years. The study isn’t peer-reviewed yet and can only show association, not causation, but it adds to growing questions about the long-term cardiovascular safety of sugar alcohols and calls for further research.

Most sugar substitutes disrupt gut bacteria and trigger surprising drug interactions
science28 days ago

Most sugar substitutes disrupt gut bacteria and trigger surprising drug interactions

A Cambridge study tested 39 sweeteners against 25 gut bacteria and found that roughly 75% affected at least one strain; mixing sweeteners with common compounds (caffeine, vanillin, and the antidepressant duloxetine) produced over 100 new interactions, some disruptive, suggesting sugar substitutes can alter the gut microbiome and interact with medications; the WHO notes non-sugar sweeteners show no proven long-term weight‑loss benefits.

Splenda and Health: What We Actually Know About Sucralose
health1 month ago

Splenda and Health: What We Actually Know About Sucralose

Sucralose (Splenda) is a calorie-free sweetener about 600 times sweeter than sugar, approved by the FDA in 1998 and generally considered safe; it can help reduce calories and manage diabetes, but animal studies have raised concerns about gut health and metabolism, while human studies are inconsistent and short, so evidence isn’t conclusive. If unsure, you can swap for alternatives like stevia or monk fruit, but overall moderation and personal tolerance should guide use.

Artificial sweeteners may accelerate brain aging, study finds
health1 month ago

Artificial sweeteners may accelerate brain aging, study finds

A Brazilian study of 12,772 adults over about eight years found that higher intake of low- and no-calorie sweeteners is associated with faster cognitive decline, especially in people under 60 and those with diabetes. Six sweeteners (aspartame, saccharin, Acesulfame K, erythritol, sorbitol, xylitol) were linked to greater decline, while tagatose showed no association. The study is observational and relies on self-reported diets, so it cannot prove causation; more research is needed to confirm findings and explore alternatives to artificial sweeteners.

Artificial Sweeteners May Speed Up Cognitive Aging, Large Brazilian Study Finds
health1 month ago

Artificial Sweeteners May Speed Up Cognitive Aging, Large Brazilian Study Finds

A Brazilian study of nearly 13,000 adults over eight years found that higher intake of six common artificial sweeteners (aspartame, saccharin, acesulfame K, erythritol, xylitol, sorbitol) was linked to faster cognitive decline; tagatose showed no such effect. The highest consumers declined about 62% faster than the lowest, roughly equating to 1.6 extra years of aging, with stronger effects in adults under 60 and those with diabetes. The study is observational and relies on self-reported intake, so it shows associations, not causation.

Zero-calorie sweeteners tied to faster brain aging in adults
health1 month ago

Zero-calorie sweeteners tied to faster brain aging in adults

A Brazilian study of 12,772 adults followed for about eight years found that higher consumption of seven low- or no-calorie sweeteners (aspartame, saccharin, acesulfame K, erythritol, sorbitol, xylitol, and tagatose) was associated with faster declines in overall cognition and memory, especially in people under 60 and those with diabetes; the strongest link showed about 62% faster decline (roughly 1.6 extra years of aging) for the highest vs lowest intake, with six sweeteners linked and tagatose not; the study shows association, not causation, and relies on self-reported data, so more research is needed and alternatives like unprocessed sweeteners may be worth considering.

Sweeteners May Have Hidden Metabolic Costs, New Analysis Finds
health2 months ago

Sweeteners May Have Hidden Metabolic Costs, New Analysis Finds

A review of 21 randomized trials links artificial and low-calorie sweeteners to higher fasting insulin and HbA1c, with a possible reduction in insulin sensitivity; gut microbiome changes may be involved, and higher consumption could relate to greater cardiometabolic risk, though causality isn’t proven. While avoiding large amounts of added sugar is prudent, replacing sugar with these sweeteners may be better than sugar, but not risk-free.