Mapping Yeast Genomes to Predict Trait Variations and Mutations
TL;DR
This study assembled near telomere-to-telomere genomes for 1,086 yeast isolates, revealing extensive structural variation and gene content diversity, and demonstrated that structural variants are more frequently associated with phenotypic traits and exhibit greater pleiotropy than SNPs, significantly advancing our understanding of the genetic basis of phenotypic diversity in yeast.
Topics:sciencebiology#biology#genotype-to-phenotype#long-read-sequencing#pangenome#structural-variants#yeast-genomes
- From genotype to phenotype with 1,086 near telomere-to-telomere yeast genomes Nature
- Yeast genomes show how large genomic variations affect trait diversity Nature
- From Genomes to Traits: 1,086 Yeast Mapped Bioengineer.org
- Yeast cells © Charité | Jakob Vowinckel (IMAGE) EurekAlert!
- Researchers Discover Method to Predict Effects of Yeast Gene Mutations Through Proteome Analysis SSBCrack
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