Aging Joint Breakthrough: Blocking 15-PGDH Rebuilds Cartilage
TL;DR
Stanford researchers showed that inhibiting the aging-related enzyme 15-PGDH reverses cartilage aging in mice, regenerating cartilage and improving gait; human knee tissue also exhibits regeneration signs, suggesting a potential new osteoarthritis therapy with clinical trials possible within 18 months, and crucially without relying on stem cells.
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