Tag

Arrhythmias

All articles tagged with #arrhythmias

Lilly’s next-gen obesity drug shows weight loss potential but safety signals need more data
health1 month ago

Lilly’s next-gen obesity drug shows weight loss potential but safety signals need more data

Lilly’s obesity drug retatrutide, which previously showed rapid weight loss and diabetes benefits, yielded new safety data at the ADA meeting and in Lancet: in TRANSCEND-T2D-1, 7 of 403 participants on retatrutide had arrhythmias and 3 had major cardiovascular events versus none on placebo, a small event count that experts say is insufficient to draw firm cardiovascular risk conclusions.

Revealing the Heart's Hidden Nervous System: A Mini-Brain Discovery
science1 year ago

Revealing the Heart's Hidden Nervous System: A Mini-Brain Discovery

New research from Karolinska Institutet and Columbia University reveals that the heart has its own complex nervous system, or "mini-brain," capable of independently regulating the heartbeat. This discovery, made through studies on zebrafish, challenges traditional views and could lead to new treatments for heart diseases like arrhythmias. The study highlights the heart's neural network's complexity and its potential interaction with the brain during stress or disease, offering new therapeutic targets.

Advancements in Heart Repair: Gene Editing and Infected Heart Transplants
health3 years ago

Advancements in Heart Repair: Gene Editing and Infected Heart Transplants

Scientists have used gene editing to create heart muscle cells that reduce arrhythmias by 95% in pigs, according to a study in the journal Cell Stem Cell. Researchers at the University of Washington discovered that cardiomyocyte injections cause arrhythmias because the cells are immature, so they fail to harmonise with the heart’s electrical system and force the organ to beat too quickly. The scientists started with human embryonic stem cells, which have the potential to become any of the 200 different cell types in the body, and altered different combinations of genes to create the new cells.