Tag

Brown Adipose Tissue

All articles tagged with #brown adipose tissue

science2 hours ago•82 min saved

Brown fat–generated microRNAs map an inter-organ metabolic circuit via secreted carriers

Using brown-fat–specific 4-thiouracil labelling, researchers traced how brown fat secretes microRNAs in vesicles and protein-bound forms that are selectively taken up by liver, muscle, and hypothalamus. In recipient tissues these BAT-derived miRNAs enter Ago2–RISC and regulate metabolic pathways (notably miR-1a-3p targeting FoxO1 in muscle, affecting mitochondrial function). Deleting Dicer in BAT reduces circulating BAT miRNAs and disrupts tissue metabolism, revealing a defined endocrine network whereby brown fat communicates with distant organs to modulate energy homeostasis.

via Nature|

#brown-adipose-tissue #extracellular-vesicles #inter-organ-communication

health-and-science23 days ago•3 min saved

Imaging suggests tirzepatide boosts brown fat to aid weight loss

In a 24-week trial, tirzepatide significantly increased brown adipose tissue activity and volume on PET/CT and MRI compared with placebo (about 65% vs 41%), suggesting the GLP-1 drug may boost energy expenditure and promote white-to-beige fat conversion, contributing to weight loss beyond appetite suppression.

via Radiology Business|

#brown-adipose-tissue #glp-1 #health-and-science

science2 years ago•5 min saved

Debunking the Connection Between Brown Fat and Social Interaction

A study attempting to establish a non-invasive method for measuring brown adipose tissue (BAT) activity and its link to social behaviors yielded inconclusive results. The use of infrared thermography to measure BAT activity proved unreliable, contradicting previous smaller-scale studies. The study highlights the complexity of linking BAT activity with human social behaviors and attachment styles, emphasizing the need for alternative methods to explore this relationship further.

via Neuroscience News|

#attachment-style #brown-adipose-tissue #infrared-thermography

health2 years ago•3 min saved

"UCLA Unveils Groundbreaking Method to Combat Obesity: Activating Brown Fat"

Researchers at UCLA have discovered nerve pathways that supply brown adipose tissue (BAT), a type of tissue that releases energy from fat metabolism as heat. This finding could potentially lead to new treatments for obesity and related metabolic conditions. By understanding and manipulating these nerve pathways, researchers hope to activate BAT and stimulate fat-burning heat, offering a targeted approach to weight loss solutions. The study, published in PLOS ONE, provides a first step towards using BAT therapeutically and finding long-term solutions for obesity.

via SciTechDaily|

#brown-adipose-tissue #health #nerve-pathways

health3 years ago•3 min saved

The Mysterious Link Between Cold Exposure and Metabolism

New research challenges the prevailing belief that brown adipose tissue (BAT) is responsible for the metabolic benefits of cold exposure. A team of Canadian researchers argues that skeletal muscles, not BAT, are the primary heat generator and drive the metabolism of glucose and lipids in cold temperatures. While BAT has been linked to lower body mass indices and improved metabolic health, it is only detectable in a small percentage of adults even in cold conditions. The researchers suggest that a more integrated perspective is needed, focusing on skeletal muscles as the main organ involved in heat production and energy expenditure during cold exposure. Further research is required to understand the full impact of cold exposure on metabolism and overall health.

via ScienceAlert|

#brown-adipose-tissue #cold-exposure #health