Tag

Calcium Channel Blockers

All articles tagged with #calcium channel blockers

Second-Line BP Drug May Harm Kidneys in Diabetics, Real-World Study Finds
health2 months ago

Second-Line BP Drug May Harm Kidneys in Diabetics, Real-World Study Finds

A real-world analysis of 31,031 adults with type 2 diabetes on RAS and SGLT2 inhibitors found that those also taking dihydropyridine calcium-channel blockers had a 33% higher risk of major kidney events (≥40% decline in eGFR or progression to dialysis/kidney transplant) over a median follow-up of 3.5 years. The observational study suggests potential kidney risk with this drug class even in patients on modern kidney-protective therapies, possibly due to how DCCBs affect intraglomerular pressure. Causation can’t be established; randomized trials are needed to guide BP management in diabetic kidney disease.

Add-on calcium-channel blockers linked to faster kidney decline in type 2 diabetes
health2 months ago

Add-on calcium-channel blockers linked to faster kidney decline in type 2 diabetes

An observational study presented at a European Renal Association congress suggests dihydropyridine calcium-channel blockers (DCCBs) used as add-on therapy to standard hypertension treatment in people with type 2 diabetes may be associated with a 33% higher risk of major adverse kidney events, hinting at faster progression of diabetic kidney disease. The findings are not yet peer-reviewed and could be affected by confounding, so replication is needed before changing guidelines. Clinicians should individualize blood‑pressure management and consider alternatives like thiazide diuretics, while patients should consult their doctors for personalized therapy.

MD Warns: BP Pills May Cause Fatigue and What to Avoid
health7 months ago

MD Warns: BP Pills May Cause Fatigue and What to Avoid

Nearly half of U.S. adults have high blood pressure, and among medications, ARBs are considered the best long-term option due to their safety profile, while beta blockers are generally less favored unless specific conditions warrant their use. Lifestyle changes like exercise, sleep, and sodium reduction are crucial for effective blood pressure management.

Amlodipine, a Common Hypertension Drug, Found Safe in Study
health2 years ago

Amlodipine, a Common Hypertension Drug, Found Safe in Study

A new study published in the journal Function has found that amlodipine, a commonly prescribed drug for treating hypertension, is not dangerous for patients. Concerns had been raised about the drug's potential risks, but the study's authors discovered that amlodipine does not activate calcium channels as previously thought. The researchers concluded that amlodipine should remain a first-line treatment for high blood pressure, as removing it could lead to a significant increase in deaths from hypertension.