Tag

Dna Changes

All articles tagged with #dna changes

health20 days ago•6 min saved

DNA clues could forecast blood cancer progression years before diagnosis

A small study of 30 patients with myeloproliferative neoplasms found that new DNA changes in blood cells often appeared years before routine tests showed progression, with stable disease showing little genetic change and cases advancing toward myeloid leukemia. Some participants developed AML, while others remained stable; patterns were also linked to common treatments (hydroxyurea and azacitidine) but did not prove causation. The findings are associative and limited by size, yet suggest that serial DNA monitoring could enable earlier, more personalized monitoring and potentially guide future targeted interventions.

via Fox News|

#blood-cancer #dna-changes #early-detection

health2 years ago•4 min saved

"DNA Damage: The Similar Threat of Vaping and Smoking"

A new study in the journal Cancer Research suggests that vaping may cause epigenetic changes in cells similar to those seen in smokers, potentially indicating negative health impacts. While it doesn't directly establish a causal effect, the study found epigenomic changes in the cells of e-cigarette users, including those who had smoked fewer than 100 cigarettes in their lives. Experts caution that further research is needed to understand the effects of e-cigarettes on human health and their potential links to cancer.

via Newsweek|

#cancer-risk #dna-changes #epigenetic-changes

health2 years ago•4 min saved

"Smoking and DNA Changes: A Multiethnic Study"

A large-scale study funded by the National Institutes of Health explored the link between smoking and DNA methylation across six racial and ethnic groups, identifying 408 DNA methylation markers related to smoking, including two that differed depending on race or ethnicity. The study, published in the American Journal of Human Genetics, used data from 2,728 participants and found that smoking was linked to DNA methylation at 408 sites, with two sites showing significant risk differences based on race or ethnicity. The findings could lead to better prediction, early detection, and treatment for smoking-related conditions, as well as improve understanding of why some populations face a higher lung cancer risk than others.

via Medical Xpress|

#dna-changes #epigenetics #health

health3 years ago•6 min saved

New report reveals breakthrough in understanding recurring UTIs.

A new report published in Nature Microbiology suggests that urinary tract infections (UTIs) can change the DNA in the cells lining the urinary tract, making them more susceptible to repeated infections. The study found that cells from mice that were susceptible to recurrent UTIs had smaller cell size and defects in differentiation, and even the DNA itself had been changed as a consequence of the initial UTI. While further work needs to be done to figure out if this is happening in humans, the researchers claim that this model is a good one.

via NPR|

#antibiotics #dna-changes #health