Tag

Early Life Stress

All articles tagged with #early life stress

health29 days ago•41 min saved

Childhood Trauma Rewires Gut Signaling via New Brain–Gut Pathways

Two Gastroenterology studies link early-life stress and prenatal exposure to serotonin-altering medications with changed gut-brain signaling and increased digestive symptoms. In mice, gut-specific serotonin signaling and the vagus nerve modulate anxiety, pain, and motility, with sex hormones shaping sex-dependent effects; in humans, large datasets show maternal depression and early adversity double the risk of functional GI disorders and GI symptoms in children. While observational, findings highlight potential gut-focused treatments and the importance of supporting maternal mental health to protect gut–brain health in offspring.

via PsyPost|

#childhood-trauma #early-life-stress #gut-brain-axis

health2 years ago•4 min saved

The Genetic Impact of Childhood Stress Surpasses Brain Injury

Early-life stress has a greater impact on gene expression in the brain than a head injury, according to a study conducted on rats. Researchers found that stress changed the activation level of many more genes in the brain compared to a traumatic brain injury. The study suggests that early-life stress may have long-lasting health consequences and highlights the importance of addressing adverse childhood experiences. The findings also revealed that stress and head injury together had different effects on brain signaling pathways, including those related to oxytocin, a hormone linked to social bonding. The study emphasizes the need for interventions and support to mitigate the detrimental effects of early-life stress.

via Medical Xpress|

#animal-study #brain-development #early-life-stress

neuroscience2 years ago•4 min saved

The Impact of Early-Life Stress on Gene Expression in the Brain

Early-life stress has a greater impact on gene expression in the brain than a head injury, according to a study conducted on rats. Researchers found that stress changed the activation level of many more genes in the brain compared to a concussion-like head injury. The study suggests that early-life stress may have long-lasting health consequences that are not fully understood. The findings highlight the importance of addressing adverse childhood experiences and providing social support and enrichment to mitigate the effects of early-life stress.

via The Ohio State University News|

#brain-development #early-life-stress #gene-expression

health2 years ago•4 min saved

"Surprising Aggression Side Effects of Ketamine Revealed in Early Life Stress Rodent Models"

New research published in Behavioral Neuroscience reveals that ketamine, a potential treatment for psychiatric disorders such as PTSD, depression, and anxiety, can increase aggression in rodent models of early life stress. The study found that while ketamine did not significantly affect other behavioral measures related to mood disorders, such as fear memory, anxiety-like behavior, and depression-like behavior, it specifically heightened aggressive behavior. These findings highlight the need for caution and further investigation before prescribing ketamine, especially in cases associated with early life traumatic experiences. However, the study was conducted in mice, and more research is needed to determine the direct applicability to humans.

via PsyPost|

#aggression #behavioral-neuroscience #early-life-stress

neuroscience3 years ago•6 min saved

Friendship: A Powerful Counter to Early Life Stress.

Strong social bonds formed in adulthood can counteract the negative effects of adversity experienced early in life, according to a study of nearly 200 baboons in Kenya. Baboons who formed strong friendships were found to reclaim up to two years of life expectancy, despite experiencing early life challenges. Each additional hardship a baboon experienced in early life translated to 1.4 years of life lost, irrespective of the strength of their social bonds. The study provides a new perspective on the capacity for social bonds to ameliorate the long-term impacts of early life stress.

via Neuroscience News|

#adversity #baboons #early-life-stress

psychology3 years ago•3 min saved

The Long-Term Effects of Early Life Stress on Mindfulness and Cognitive Abilities.

A study by researchers in Brazil found that individuals who experienced early life stress often had high scores on certain aspects of trait mindfulness, such as nonreactivity and awareness. While early life stress can lead to negative health outcomes, mindfulness-based interventions can promote healthy functioning and build resilience. The study suggests that mindfulness training could be a useful approach for stress management and emotional regulation in those who have a history of early life stress.

via PsyPost|

#early-life-stress #emotion-regulation #mental-health