Donor eggs can’t reset the aging uterus, fertility falls after 49
A study of 1,774 women found that while younger donor eggs raise IVF chances for some, women aged 49 and older still face lower pregnancy and live-birth rates and higher miscarriage risk. Pregnancy chances drop from about 54% in younger women to ~43% at 49+, live births fall from ~46% to ~32%, and miscarriage rises from 24% to 38%, suggesting age-related changes in the womb lining (endometrium) may limit the benefit of donor eggs. The findings don’t discourage donor-egg treatments but highlight that aging of the uterus matters and should be discussed with patients.
