Tag

Placenta

All articles tagged with #placenta

Placenta-Derived Vesicle Nasal Spray Improves Cognition in Alzheimer’s Mouse Model
science24 days ago

Placenta-Derived Vesicle Nasal Spray Improves Cognition in Alzheimer’s Mouse Model

A Translational Neurodegeneration study in mice shows that a nasal spray containing extracellular vesicles derived from human placenta (hAMSC-EVs) reached the hippocampus and improved cognitive performance in Alzheimer's-model mice after six months of twice-weekly dosing. The treatment reduced amyloid-beta deposits and neuroinflammation, and increased neuroplasticity markers (ARC, GluA1, BDNF), though it did not affect tau phosphorylation. Separate experiments with patient-derived neurons suggested neuroprotective effects. Researchers emphasize this is preclinical and human efficacy is unproven, but placenta-derived EVs could represent a promising direction pending further study.

Placenta Rights: Why Birth Plans Should Include Disposal Choices
health3 months ago

Placenta Rights: Why Birth Plans Should Include Disposal Choices

The Conversation argues placenta disposal should be discussed during pregnancy rather than treated as a postbirth disposal issue. Cultural meanings of the placenta vary globally, and discussing options—such as taking the placenta home, burial, or safe disposal—with midwives can respect cultural beliefs, reduce distress, and improve safety. UK NHS guidelines vary, but proactive discussions within birth planning can ensure women’s choices are informed and supported.

Ancient viral DNA helped shape the human placenta
science4 months ago

Ancient viral DNA helped shape the human placenta

About 8% of the human genome is derived from ancient retroviruses; some of these viral sequences, notably the syncytin genes, have been repurposed to drive placental formation, with decisive knockout data in mice and strong but inferential evidence in humans; across mammals, multiple independent viral captures suggest placental evolution repeatedly borrowed viral tools rather than a single origin.

Pregnancy-specific cell type found at maternal-fetal interface may regulate placental invasion
health6 months ago

Pregnancy-specific cell type found at maternal-fetal interface may regulate placental invasion

Live Science reports a Nature study that created a single-cell atlas of placental and uterine tissues from weeks 5–39 of pregnancy, analyzing about 1.2 million cells and identifying a previously undescribed pregnancy-only cell type, decidual stromal cell 4 (DSC4), at the maternal–fetal interface. DSC4 appears to help regulate fetal invasion into the uterus and arteries and carries cannabinoid receptors, a finding that could help explain cannabis-associated risks in pregnancy. By linking cell activity to genes tied to preeclampsia, preterm birth, and pregnancy loss, the atlas highlights which cells may drive complications and offers new targets for future research and therapies.

CDC Updates COVID Vaccine Guidelines Amidst R.F.K. Jr. Controversy
health1 year ago

CDC Updates COVID Vaccine Guidelines Amidst R.F.K. Jr. Controversy

The article discusses the importance and safety of COVID vaccination during pregnancy, highlighting that pregnant women are at higher risk of severe illness and complications from COVID, including effects on the placenta and increased risk of blood clots. Despite some recent policy changes removing the vaccine from recommended schedules for pregnant women, scientific evidence supports vaccination to protect both mothers and infants, with ongoing research emphasizing its benefits. The article also notes concerns about reduced surveillance and access issues due to policy shifts.

"Uninfluential Black Hole and Adorable Bug: Saturday's Galactic Discoveries"
astronomy-and-biology2 years ago

"Uninfluential Black Hole and Adorable Bug: Saturday's Galactic Discoveries"

Researchers study an anemic blue compact dwarf galaxy, I Zwicky 18, using the James Webb Telescope, finding extreme populations of massive stars and large supershells of dust and ionized gas. A new genus of fluffy longhorn beetle, Excastra albopilosa, is discovered in Australia, possibly evolving its fuzzy coat as a predator deterrent. Astronomers report that quasar H1821+643, located 3.4 billion light-years from Earth, has little influence on its surroundings compared to other black holes. Duke University researchers develop a technique to capture high-definition images of mouse placental development, tracking blood vessel size and density, and oxygen levels from early to late pregnancy stages.

"Alarming Discovery: Microplastics and Toxic Chemicals Found in Human Placentas"
health-and-environment2 years ago

"Alarming Discovery: Microplastics and Toxic Chemicals Found in Human Placentas"

Scientists have discovered microplastics in all 62 human placentas they examined, with polyethylene being the most frequently detected type. This finding raises concerns about the potential impact on human health, as microplastics have been linked to DNA damage, immune and metabolic system issues, and other health problems. The discovery is particularly worrying as the placenta develops over a short period during pregnancy. Efforts to limit exposure to microplastics and reduce plastic waste are underway, with solutions including specialty water filters and plastic-eating bacteria, but rethinking our relationship with plastic and switching to reusable alternatives is crucial to address this concerning issue.