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Engram

All articles tagged with #engram

Engram banks $98M to slash AI costs with memory-first models
technology18 days ago

Engram banks $98M to slash AI costs with memory-first models

Engram, a memory-focused AI startup, raised $98M from major investors including General Catalyst, Kleiner Perkins, Sequoia and OpenAI cofounder Karpathy, claiming its 'learned memory' tech can recall company-specific context to deliver cheaper, smarter outputs—reportedly matching or beating frontier labs with up to 100x fewer tokens—and plans to deploy the funds to grow compute and talent for enterprise clients like Microsoft, Notion and Harvey.

Targeted cellular reprogramming restores memory in aging mice
science4 months ago

Targeted cellular reprogramming restores memory in aging mice

Researchers used a brief, targeted OSK gene-therapy to partially reprogram engram neurons—memory traces activated during learning—in aged mice. By activating OSK specifically in hippocampal and prefrontal engrams, they reset aging-related cellular features, restoring both recent and remote memories and improving spatial learning, including in Alzheimer’s-model mice, without disrupting overall brain identity or performing a whole-brain reboot—a proof-of-concept for cognitive rejuvenation.