Tag

Er 100

All articles tagged with #er 100

Eye-Aging Reprogramming Trial Doses First Patient in Vision Rescue Study
science2 months ago

Eye-Aging Reprogramming Trial Doses First Patient in Vision Rescue Study

Life Biosciences dosed the first patient in a small, safety-focused trial of ER-100, a gene therapy designed to reset epigenetic marks in retinal ganglion cells to reverse aging-like changes and potentially restore vision in open-angle glaucoma or NAION. Delivered by a virus and activated by a specific antibiotic, the study will enroll up to 18 participants and follow them for years, attracting both optimism about aging biology and warnings about safety risks and uncertain efficacy.

First Patient Dosed in Eye-Targeted Cellular Reprogramming Anti-Aging Trial
health2 months ago

First Patient Dosed in Eye-Targeted Cellular Reprogramming Anti-Aging Trial

Life Biosciences dosed the first patient in a human trial of ER-100, a cellular reprogramming therapy designed to make aging cells act younger; the injection targeted the eye for glaucoma and uses three of the Yamanaka factors with a doxycycline switch to control activity. If safe and effective, it could open the door to systemic anti-aging therapies, but cancer risk remains a concern. The study will monitor safety over six months with up to about 20 participants enrolled across multiple cities.