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Folate Deficiency

All articles tagged with #folate deficiency

Folate Deficiency: A Hidden Driver of Fatigue, Headaches, and Cognitive Hurdles
health6 days ago

Folate Deficiency: A Hidden Driver of Fatigue, Headaches, and Cognitive Hurdles

Folate deficiency can cause fatigue and headaches by leading to anemia and reduced oxygen delivery, and it may also impair memory and cognitive function. True folate deficiency is rare in the US thanks to food fortification and a varied diet, though it can accompany other nutrient gaps. Folate is found in leafy greens, beans, and fortified foods, and alcohol consumption can worsen risk when intake is low. Addressing overall nutrition and hydration is important if fatigue, headaches, or memory concerns arise.

Folate Deficiency: Fatigue, Headaches, and Memory Trouble Explained
wellness12 days ago

Folate Deficiency: Fatigue, Headaches, and Memory Trouble Explained

Folate deficiency can cause anemia leading to fatigue and shortness of breath, and, if prolonged, headaches and memory problems; while rare in the U.S. thanks to fortified foods, risk rises with chronic alcohol use and malabsorption conditions (such as celiac disease or inflammatory bowel disease), and pregnancy increases folate needs. Most people meet folate needs through a varied diet—leafy greens, beans, and fortified cereals—so a deficiency is uncommon, but a serum folate test can confirm if symptoms like fatigue, headaches, or memory issues persist. If considering supplements, talk to a clinician and avoid exceeding 1,000 micrograms daily; dietary folate equivalents are used to gauge absorption, with better uptake when taken with food.

Megaloblastic Anemia Masquerading as Hemolysis in Chronic PPI Therapy: Two Case Reports
hematology1 month ago

Megaloblastic Anemia Masquerading as Hemolysis in Chronic PPI Therapy: Two Case Reports

Two middle-aged women on long-term proton pump inhibitors presented with severe macrocytic anemia and biochemical signs suggestive of hemolysis (very high LDH, undetectable haptoglobin) but showed a low reticulocyte count. Workup revealed combined vitamin B12 and folate deficiency causing ineffective erythropoiesis that mimicked hemolysis. Vitamin replacement and cessation of PPI therapy led to rapid clinical and hematologic improvement, highlighting that B12/folate deficiency can resemble hemolytic processes and that PPI use may contribute to B12 deficiency.

The Surprising Link Between Vitamin Deficiency and Joint Hypermobility.
health3 years ago

The Surprising Link Between Vitamin Deficiency and Joint Hypermobility.

Tulane University researchers have discovered a possible genetic cause for hypermobility and related disorders, such as Ehlers-Danlos syndrome, linking it to a deficiency of folate caused by a variation of the MTHFR gene. The discovery could help doctors diagnose hypermobility and hypermobile EDS more accurately by looking for elevated folate levels in blood tests and the MTHFR genetic variant. An existing FDA-approved treatment, methylated folate, has shown promise in improving patients’ symptoms.

The Link Between Vitamin Deficiency and Hypermobile Ehlers-Danlos Syndrome.
health3 years ago

The Link Between Vitamin Deficiency and Hypermobile Ehlers-Danlos Syndrome.

Researchers at Tulane University School of Medicine have linked hypermobility and hypermobile Ehlers-Danlos Syndrome to a deficiency of folate caused by a variation of the MTHFR gene. The discovery could help doctors more accurately diagnose hypermobility and hypermobile EDS by looking for elevated folate levels in blood tests as well as the MTHFR genetic variant. The good news is that a treatment already exists, methylated folate, which is FDA-approved and widely available.