Tag

Hematology

All articles tagged with #hematology

business17 days ago•26 min saved

Merck to buy Terns to accelerate CML program with allosteric inhibitor TERN-701

Merck will acquire Terns Pharmaceuticals for about $6.7 billion in cash, expanding its hematology portfolio with TERN-701, an oral allosteric BCR-ABL1 inhibitor in Phase 1/2 for Philadelphia chromosome-positive chronic myeloid leukemia (CML). The transaction, approved by both boards, is expected to close in the second quarter of 2026 and will be accounted as an asset acquisition with an approximate $5.8 billion impact on 2026 GAAP/non-GAAP results. TERN-701 has shown encouraging early activity and carries FDA Orphan Drug Designation from 2024, underscoring its potential as a differentiated CML therapy.

via Merck.com|

#business #cml #hematology

science2 months ago•8 min saved

Scientists Reveal MAL Blood Group, Paving Precision Transfusions

A UK–Israel team identifies the MAL blood group system, linked to mutations in the MAL gene that remove the AnWj antigen; traced to a 1972 case and published in Blood (2024). This new blood type could improve matching for rare donors and enable tests to distinguish inherited versus antigen-suppression causes, potentially advancing transfusion medicine and patient care.

via Indian Defence Review|

#blood #genetics #hematology

health2 years ago•3 min saved

Platelet transfusion policy reaches bottom with new NEJM study.

Researchers from Amsterdam UMC and eight other Dutch hospitals have found that being increasingly restrictive in preventive blood transfusion is not always understandable. The study focused on whether a platelet transfusion is necessary to be able to insert a catheter safely. Patients with very few platelets actually have less bleeding if they are transfused prior to CVC placement. The researchers suggest that any possible cost savings should always be properly investigated and that the cost-benefit assessment can work out differently for different patients.

via Medical Xpress|

#blood-transfusion #health #hematology

business2 years ago•1 min saved

Sobi acquires CTI BioPharma for $1.7 billion.

Swedish Orphan Biovitrum (Sobi) has agreed to acquire US biotech CTI BioPharma for $1.7bn, in a deal that will be funded by debt financing from Bank of America and Danske Bank. Sobi's main shareholder, Investor AB, has agreed to subscribe for its pro-rata share of the rights issue, corresponding to about 34.7% of the shares to be issued. The acquisition will fit well with Sobi's focus on hematology and will deliver a medicine that's already cleared for sale in the US market. However, Sobi's shares plunged as much as 17% in early trading after the company said it would acquire all of CTI's outstanding stock for $9.10 per share, almost double CTI's last closing price, and issue new shares to fund as much as half of the transaction.

via Yahoo Finance|

#acquisition #business #cti-biopharma