The Cincinnati Reds defeated the St. Louis Cardinals 10-9 in a back-and-forth game, riding a five-run sixth inning and four more in the ninth to build a lead that the Cardinals nearly erased with a six-run rally in the bottom of the ninth.
The Braves were held to a lone run in a 4-1 defeat to the Twins in Minneapolis. Tyler Mahle limited Atlanta to two early runs in 6.2 innings, while Dodd and the bullpen allowed two insurance runs in the eighth. Drake Baldwin provided the only Braves offense with a sixth‑inning homer, and Matt Olson was the sole bright spot among hitters as Atlanta’s slumping bats continued into the series.
The Twins jumped on the Braves with a four-run first inning and rode a steady pitching effort to a 4-2 win at Target Field, as Atlanta failed to homer and left several balls on the warning track with seven opposite-field outs. Martin Perez worked five innings, allowing four runs, while the Braves finally scratched across a run in the fifth on Riley, Baldwin and Acuña Jr., but couldn’t complete the comeback as the Twins bullpen locked it down.
Detroit jumped out to an early lead and withstood a late Pirates rally to beat Pittsburgh 8-5. Pirates starter Carmen Mlodzinski struggled, issuing seven walks, while Detroit’s Framber Valdez earned the win despite some hiccups. Tigers' Kevin McGonigle opened the scoring with a two‑run homer, and Pittsburgh answered late with Nick Yorke’s three‑run double and Callahan’s two‑run single, but Detroit’s bullpen closed it out as the Tigers moved to 60-64 and the Pirates dropped to 61-65.
The Patriots and Colts tied 13-13 in New England’s preseason opener at Gillette, with Kyle Williams delivering the first Pats TD after a clean release and showing big-play potential, Eli Raridon flashing explosiveness despite a modest box score, and John Saunders Jr. snagging an interception. Negative notes included Andy Borregales going 2-for-5 on field goals (including a late miss) and concerning guard-depth injuries to Ben Brown, Andrew Rupcich, James Hudson, and Mehki Butler. Rookies Caleb Lomu and Jacas made positive impacts, Jam Miller led the backfield with 14 carries for 55 yards, and several other young players showed flashes in a game that exposed some depth issues.
The Reds hold off the White Sox 9-8 in a chaotic game that saw Davis Martin ejected after hitting Sal Stewart, Stephenson slug a three-run homer to stretch Cincinnati’s lead, and Tanner McDougal make his MLB debut by walking three and hitting a batter with the bases loaded to help seal the win as Chicago staged a late rally that fell short.
The Milwaukee Brewers defeated the Pittsburgh Pirates 4-2 at American Family Field to improve to 69-43 while Pittsburgh falls to 57-57. Henderson worked six solid innings for the win, limiting the Pirates to four hits and two runs while fanning eight; Jared Jones lasted four innings with three earned runs allowed. Pittsburgh grabbed an early lead on Endy Rodriguez’s solo homer, but Milwaukee answered with Chourio’s tying homer, Vaughn’s solo shot, and Lara’s RBI single in the fifth for insurance. The Pirates were held to five hits, Pirates reliever Kirby Yates debuted in the eighth, Brewers reliever Antonio Senzatela appeared in the seventh in his Brewers debut, and Don Kelly was ejected after arguing a strike call.
After Jameson Taillon’s command woes and an early Pirates onslaught that produced two homers and a grand slam to build a 7-1 lead, the Cubs mounted a furious rally with Pedro Ramirez and PCA delivering key hits and Seiya Suzuki’s late two-run homer tightening the gap. Chicago came up short in the final at-bat as Michael Busch grounded out and Ian Happ struck out, leaving the Pirates ahead 8-7. Pedro Ramirez earned Player of the Game honors, extending his hitting streak to seven games and fueling questions about his future role alongside Cubs youngsters.
Samuel Basallo delivered a go-ahead two-run homer in the eighth to lift the Baltimore Orioles to a 5-3 win over the Kansas City Royals in the opener of a three-game set. Blaze Alexander also homered for Baltimore, while Kansas City's J. Caglianone and I. Collins answered with solo shots. Brandon Young went seven innings for Baltimore, Rico Garcia earned the win, and Andrew Kittredge notched the save as Royals relievers faltered in the late frame; M. Strahm took the loss for Kansas City.
Pete Crow-Armstrong homered twice as the Cubs slugged five homers in a 9-7 win over the Orioles. Conforto and Kelly also went deep early, tying the game after Baltimore grabbed a 3-1 lead on Alonso’s two-run shot, then Chicago exploded for five runs in the seventh highlighted by Suzuki’s three-run homer. Tyler O’Neill homered twice for Baltimore and Coby Mayo added a homer, but the Cubs held on as Jacob Webb earned the save. Colin Rea earned the win for Chicago, Colin Kremer took the loss for Baltimore. Crow-Armstrong became MLB’s first 20-homer, 20-steal player this season, and the Cubs will try to complete the three-game sweep tomorrow with Peterson facing Rogers.
In San Francisco, the Giants edged the Braves 3-2 as Atlanta’s defense cost them an unearned run and a late ninth-inning rally fell short; Chris Sale logged six solid innings with 10 strikeouts for Atlanta while Robbie Ray went eight strong for the Giants, and timely hits plus a miscue-filled frame sealed the Braves’ latest series loss.
Chicago turned a 1-1 tie into a six-run sixth, highlighted by Sam Antonacci’s tying homer and Colson Montgomery’s two-run shot, followed by Braden Montgomery’s RBI single and Chase Meidroth’s three-run homer to drive the White Sox to a 6-1 lead. Erick Fedde worked into the sixth in a bullpen-game performance, and Seranthony Domínguez closed the ninth to finish off a 6-4 win over the Dodgers, securing the series victory and keeping Chicago in a first-place tie.
The Chicago White Sox erupted for a seven-run fifth inning to rout the Los Angeles Dodgers 8-2, extending their hot stretch against elite teams to three straight wins. Anthony Kay earned the win with five solid innings as Dodgers ace Roki Sasaki faltered in the fifth, and Sox hitters sealed it with Meidroth’s two-run single and Peters’ two-run triple, in front of a sellout crowd of 37,882.
Edmundo Sosa redeemed a late pinch-hit gamble from Phillies manager Don Mattingly by belting a go-ahead two-run homer off Tanner Scott in the eighth, lifting Philadelphia to a 4-3 comeback win over the Dodgers at Dodger Stadium.
Milwaukee defeated St. Louis 4-1 on May 25, 2026, jumping out to a 3-0 lead in the first thanks to Christian Yelich’s first-inning homer and a run-scoring play. The Cardinals finally pushed across a run in the sixth, but Milwaukee added a run in the sixth and another in the seventh to pull away. Starting pitchers were J. Misiorowski for the Cardinals and M. Liberatore for the Brewers, with the bullpen finishers contributing in relief.