Tag

Gba1

All articles tagged with #gba1

Gut microbes may foretell Parkinson's years before symptoms
health4 months ago

Gut microbes may foretell Parkinson's years before symptoms

Researchers from UCL analyzed gut microbes in more than 1,400 participants across the UK, Korea, and Turkey and found distinct microbiome patterns linked to Parkinson's risk, including in non-symptomatic GBA1 carriers; a diverse diet correlated with lower risk profiles, but the study is observational and cannot prove causation, though it supports the gut-brain axis as a potential avenue for early detection and treatment.

Gut Microbes Signal Parkinson’s Risk Years Before Symptoms
science4 months ago

Gut Microbes Signal Parkinson’s Risk Years Before Symptoms

A multi-cohort study finds a distinctive gut microbiome signature that distinguishes people with Parkinson’s and healthy individuals at genetic risk (including GBA1 carriers without symptoms), suggesting the gut microbiome could serve as an early warning and preventive target. Findings replicated across UK, Korea, and Turkey with over 1,400 participants; diet diversity may influence risk, and UCL-led trials are testing gut-targeted therapies, including using a common cough medicine, to slow progression.