Tag

Immune Dysregulation

All articles tagged with #immune dysregulation

health2 months ago•6 min saved

Long COVID May Set Off New Allergies Through Immune Dysregulation

New evidence suggests long COVID is associated with persistent immune dysregulation that may drive new allergic conditions. Studies link SARS-CoV-2 infection to higher risks of asthma, allergic rhinitis, and chronic rhinosinusitis, with vaccination offering protection. Some researchers also point to mast cell activation syndrome as part of long COVID's allergic manifestations. Clinicians report anecdotal and clinic-based increases in allergies post-COVID and call for early screening, biomarker research, and prospective trials to prevent or modify these outcomes.

via Medscape|

#allergies #asthma #health

health2 years ago•4 min saved

"Mitochondrial Role in Exercise Intolerance for Long COVID Patients Revealed in Study"

A recent study published in Nature Immunology reveals that long COVID patients exhibit T cell dysregulation, inflammation, and an uncoordinated adaptive immune response to SARS-CoV-2, as evidenced by blood sample analysis using 'omics' approaches and serological assays. The findings suggest that immune-associated changes and phenotypic alterations in T cells and other immune cells may underlie the persistent and wide-ranging symptoms associated with long COVID, potentially due to miscommunication or error in crosstalk between humoral and cellular adaptive immunity involving B and T cells.

via News-Medical.Net|

#health #immune-dysregulation #inflammation

neurology2 years ago•3 min saved

"Insights into Long COVID: Immune Dysregulation, Genetic Impact, and CBT Benefits"

A small cohort study conducted by the National Institute of Neurological Disorders and Stroke (NINDS) of the NIH in Bethesda, Maryland, found that people with long COVID neurologic symptoms had broad immune dysregulation in their cerebrospinal fluid (CSF), with lower levels of CD4+ and CD8+ T cells and increased B cells and other types of immune cells. Autonomic testing also showed dysfunction. The findings suggest that immune dysregulation may play a role in mediating long COVID and call for further investigations to confirm these changes and evaluate the role of immunomodulatory agents in clinical trials.

via Medpage Today|

#autonomic-dysfunction #cd4-t-cells #cd8-t-cells