Tag

Neoadjuvant Therapy

All articles tagged with #neoadjuvant therapy

science1 month ago•25 min saved

Neoadjuvant Immunotherapy Achieves 100% No-Recurrence in MSI-H Colorectal Cancer Trial

A small NEOPRISM-CRC trial at University College London treated stage II/III colorectal cancers with MSI-H/MMR-deficient tumors using pembrolizumab before surgery. After nearly three years of follow-up, no patient experienced cancer recurrence, suggesting neoadjuvant immunotherapy could spare or reduce chemotherapy for this 10–15% subset of bowel cancers, though larger studies are needed to confirm efficacy and applicability.

via ZME Science|

#colorectal-cancer #immunotherapy #msi-h

health2 years ago•4 min saved

"Why Some Cancer Patients, Like Kate Middleton, Need Both Chemotherapy and Surgery: An Oncologist's Perspective"

Oncologist Alexander Olawaiye explains that cancer treatment plans depend on the type and stage of cancer, with some patients receiving a combination of treatments such as surgery and chemotherapy. Factors like tumor aggressiveness, spread, and organ of origin influence the likelihood of recurrence. Adjuvant therapy, given after surgery, aims to kill any remaining cancer cells, while neoadjuvant therapy, given before surgery, can shrink tumors and reduce the extent of surgery required. These approaches, along with ongoing research, offer hope for more effective cancer treatment in the future.

via The Conversation Canada|

#adjuvant-therapy #cancer-treatment #chemotherapy

health2 years ago•40 min saved

Merck's KEYNOTE-671 Trial Shows Promising Overall Survival Results in Resectable NSCLC

Merck's Phase 3 KEYNOTE-671 trial investigating KEYTRUDA as a perioperative treatment for resectable stage II, IIIA, or IIIB non-small cell lung cancer (NSCLC) has met its dual primary endpoint of overall survival (OS). The trial demonstrated a statistically significant and clinically meaningful improvement in OS when KEYTRUDA was used as neoadjuvant therapy followed by surgery and adjuvant therapy, compared to placebo plus chemotherapy. These results mark a significant milestone in the treatment of resectable NSCLC and offer potential extended survival for patients in earlier stages of the disease.

via Merck|

#adjuvant-therapy #health #keytruda