All articles tagged with #neural tube defects
A large Chinese cohort study found that low red blood cell B12 and folate levels in both mothers and fathers around conception are associated with a higher risk of birth defects in offspring, including heart defects, suggesting paternal nutrition and possible epigenetic effects may influence fetal development and reinforcing the case for including men in preconception care.
Britain will require non-wholemeal white flour to be fortified with folic acid by the end of 2026 to help reduce neural tube defects in newborns; the government says the measure could prevent about 200 such birth defects each year and save the NHS about £20m over a decade while boosting the economy by over £90m, with expert bodies asserting the benefits outweigh potential risks. Some bakers and mills had already been adding folic acid and reactions have been mixed.
Researchers used genetically modified fluorescent quail embryos to watch neural tube formation in real time, discovering that PRICKLE1 governs up-down cell movements rather than left-right cues—an insight that could guide genetic screening and therapies for neural tube defects affecting hundreds of thousands of pregnancies annually.
Prenatal vitamins with folic acid are essential for preventing neural-tube defects, but some brands now promote methylfolate as a superior alternative due to misconceptions about synthetic folic acid. Experts emphasize that folic acid is well-proven, safe, and crucial during early pregnancy, and replacing it without solid clinical evidence could be risky. Consumers should be cautious of marketing claims and prioritize evidence-based prenatal care.
Folic acid, a B vitamin, is crucial for pregnancy as it aids in the development and maintenance of cells, particularly during the early stages when the baby's brain and nervous system are forming. It helps prevent neural tube defects and supports overall fetal development, including the growth of the brain, organs, and tissues. Adequate folic acid intake also benefits the mother by reducing the risk of anemia and preeclampsia. Pregnant women are recommended to consume 600 mcg of folic acid daily, while all women of childbearing age should supplement their diets with 400 mcg daily. Food sources rich in folic acid include beef liver, dark leafy greens, oranges, avocados, and fortified products like bread and cereals. It is important to consult with a healthcare provider before starting any supplementation.