AI Maps Dual-Speed Glymphatic Flow in the Living Brain
Researchers used physics-informed AI to infer three-dimensional brain fluid velocities from dynamic MRI, revealing two distinct glymphatic flows: a fast surface passage and a slow deep-tissue flow roughly 50 times slower. The method, demonstrated in animal models, aims to enable whole-brain fluid mapping for comparing healthy and diseased brains, with potential clinical uses in assessing brain circulation after concussion and screening for Alzheimer’s-related risks.