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Brain Fluid Dynamics

All articles tagged with #brain fluid dynamics

AI Maps Dual-Speed Glymphatic Flow in the Living Brain
science1 month ago

AI Maps Dual-Speed Glymphatic Flow in the Living Brain

Researchers used physics-informed AI to infer three-dimensional brain fluid velocities from dynamic MRI, revealing two distinct glymphatic flows: a fast surface passage and a slow deep-tissue flow roughly 50 times slower. The method, demonstrated in animal models, aims to enable whole-brain fluid mapping for comparing healthy and diseased brains, with potential clinical uses in assessing brain circulation after concussion and screening for Alzheimer’s-related risks.

Abdominal contractions trigger brain motion via a hydraulic-like mechanism, study finds
neuroscience2 months ago

Abdominal contractions trigger brain motion via a hydraulic-like mechanism, study finds

A Nature Neuroscience study in awake mice shows abdominal muscle contractions compress a network of veins called the vertebral venous plexus, pushing fluid and causing the brain to shift slightly within the skull. Using two-photon microscopy and computer simulations, researchers suggest this mechanical pumping could drive cerebrospinal fluid flow to clear waste, offering a potential mechanism for how exercise benefits brain health. The work used head-fixed mice on a spherical treadmill with abdominal pressure applied by a pneumatic belt, and notes limitations such as imaging only the top cortex and simplified anatomy, with human relevance still to be determined.