Tag

Ponesimod

All articles tagged with #ponesimod

"MS Drug Offers Hope as Alzheimer's Treatment"
health3 years ago

"MS Drug Offers Hope as Alzheimer's Treatment"

A study conducted by scientists at the University of Kentucky College of Medicine suggests that the multiple sclerosis (MS) drug ponesimod could potentially be used as a therapy for Alzheimer's disease. The researchers found that ponesimod, which inhibits neuroinflammation in MS, also reduced amyloid plaques in the brain and improved attention span and working memory in mouse models of Alzheimer's. The study highlights the potential role of neuroinflammation in Alzheimer's and suggests that drugs targeting inflammation may have therapeutic benefits for the disease. Further research and clinical trials are needed to explore the use of ponesimod as an Alzheimer's therapy.

"MS Drug Holds Potential as Alzheimer's Treatment, Scientists Find"
health3 years ago

"MS Drug Holds Potential as Alzheimer's Treatment, Scientists Find"

Ponesimod, an oral medication approved for multiple sclerosis (MS), has shown potential in treating Alzheimer's disease by blocking inflammation in the nervous system. Researchers from the University of Kentucky found that ponesimod effectively blocked overactive immune activity in a mouse model of Alzheimer's, reducing pro-inflammatory cytokines and promoting anti-inflammatory signaling. The drug's ability to reprogram microglia, brain-prowling white cells, into neuron-protective cells that clear toxic proteins in the brain shows promise for improving memory and reducing neuroinflammatory pathology. While further research is needed to confirm these findings in humans, the fact that ponesimod is already approved for MS treatment could expedite its potential use for Alzheimer's therapy.

"Multiple Sclerosis Drug Repurposed as Promising Alzheimer's Therapy"
medical-research3 years ago

"Multiple Sclerosis Drug Repurposed as Promising Alzheimer's Therapy"

Ponesimod, an FDA-approved drug used to treat multiple sclerosis, has shown promise as a potential therapy for Alzheimer's disease. The medication reduces neuroinflammation, a key factor in Alzheimer's progression, by reprogramming microglia cells to clear toxic proteins. Experiments in mouse models and human brain samples support these findings, suggesting that ponesimod could be repurposed for Alzheimer's treatment.