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Ppard

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science22 days ago

Berry-Derived Compound Shields Metabolic Regulator to Boost Muscle Fat Burn

Researchers identified pterostilbene, a polyphenol in blueberries and grapes, as stabilizing the fat-metabolism regulator PPARδ in cultured mouse skeletal muscle cells. This protection increases fatty acid oxidation and reduces intracellular fat buildup, suggesting potential dietary strategies for metabolic health, though in‑vivo studies are needed to confirm safety and efficacy before clinical use.

Blueberry-derived compound stabilizes PPARδ to boost fat breakdown in muscle cells
health1 month ago

Blueberry-derived compound stabilizes PPARδ to boost fat breakdown in muscle cells

A blueberry-derived compound, pterostilbene, stabilizes the fat-regulating protein PPARδ in skeletal muscle cells, enhancing fatty acid oxidation and reducing stored lipids by slowing PPARδ degradation. The effect was shown in cultured mouse muscle cells, suggesting potential for dietary strategies to support metabolic health, but it has not yet been demonstrated in animals or humans.