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Prif

All articles tagged with #prif

Low-fiber diets may push gut microbes to eat mucus; indigestible plant proteins could steer healthier outputs
health-and-medicine28 days ago

Low-fiber diets may push gut microbes to eat mucus; indigestible plant proteins could steer healthier outputs

When dietary fiber runs low, gut microbes may degrade the gut’s mucus lining and produce harmful phenol metabolites; however, indigestible plant proteins (Prif) along with fiber shift microbial metabolism toward beneficial phenols, while host metabolism can also generate many indole and phenol metabolites, suggesting diet- and metabolism-based strategies to modulate gut biochemistry and health.

science1 month ago

Fiber and Prif Proteins Redirect Gut Bacteria Toward Healthier Metabolites

Two Princeton-led studies show that fiber and indigestible plant proteins (Prif) steer gut bacteria away from breaking down the intestinal mucus and toward producing healthier phenylalanine-derived metabolites, while reducing harmful tyrosine-derived ones; plus host cells also produce many indoles and phenols—together shaping the body's metabolite profile and guiding nuanced nutrition and therapies.

Plant-based diets rewire gut microbes to boost beneficial metabolites
gastrointestinal-health1 month ago

Plant-based diets rewire gut microbes to boost beneficial metabolites

Two studies show plant-based diets reshape the gut microbiome by using fiber and indigestible plant proteins (Prif) to tilt bacterial metabolism toward health-promoting phenols and away from harmful ones; another study finds many indole and phenol metabolites are produced by mammalian metabolism, not only microbes. Together, the work clarifies how diet shapes microbial outputs and could guide dietary and therapeutic strategies.