Tag

Scratching

All articles tagged with #scratching

Scratch That Itch: Study Links Scratching to Longer Eczema Flare via Mast Cells
health1 month ago

Scratch That Itch: Study Links Scratching to Longer Eczema Flare via Mast Cells

University of Pittsburgh researchers found that scratching an itch triggers mast cells to release histamine and other inflammatory chemicals, increasing inflammation and prolonging the itch-scratch cycle. In mice, those allowed to scratch showed more substance P and inflammation, while preventing scratching reduced inflammation; scratching also lowered levels of Staphylococcus aureus, but the skin damage from chronic scratching likely outweighs this benefit. Cold compresses and 1% hydrocortisone can help relieve itching. The study, published in Science, sheds light on the evolutionary role of scratching in skin defense but with a caution for chronic inflammation.

Scratch That Itch: Science Explains Why It Feels Good But Worsens Bug Bites
science1 month ago

Scratch That Itch: Science Explains Why It Feels Good But Worsens Bug Bites

New mouse studies show scratching bug bites increases swelling by triggering mast cells via pain signals and histamine, creating an itch–scratch cycle. Menthol and anti-itch creams can temporarily relieve, and researchers are pursuing targeted treatments (MRGPRX2 blockers). In the meantime, avoid scratching and use hydrocortisone, calamine, or oatmeal baths to calm itch.

The itch dilemma: when scratching helps and when it hurts
health1 month ago

The itch dilemma: when scratching helps and when it hurts

A medical explainer shows that itching is caused by nerve signals and histamines; while scratching can provide relief, it often worsens the itch, damages skin, and can invite infection, especially with mosquito bites. Practical tips include cold compresses, moisturizers, anti-itch creams, oral antihistamines, trimming nails, and avoiding scratching; seek medical care for persistent or severe itching.

TRPV4 channels reveal brain’s stop-scratching signal
science3 months ago

TRPV4 channels reveal brain’s stop-scratching signal

Researchers show that TRPV4 channels in touch‑sensitive neurons participate in a negative feedback signal telling the brain scratching has provided enough relief, effectively acting as a neural “stop scratching” switch. In mice engineered to lack TRPV4 in sensory neurons, scratching episodes were fewer but lasted longer, implying that targeted neuronal pathways—not blanket TRPV4 blockade—could be key for treating chronic itch.

iPhone 17 Pro's Hidden Vulnerability to Scratches Uncovered
technology11 months ago

iPhone 17 Pro's Hidden Vulnerability to Scratches Uncovered

The iPhone 17 Pro is more resistant to scratches overall, thanks to its anodized aluminum shell, but the camera area remains vulnerable due to a sharp, raised edge that scratches easily, especially on darker finishes. Users are advised to use a case to protect the camera from scratches, while other parts of the phone are more durable against minor scratches from everyday items.

The Science Behind Unstoppable Itch Scratching
science2 years ago

The Science Behind Unstoppable Itch Scratching

The cycle of itching and scratching can be difficult to break due to the evolutionary reflex developed to expel unwanted visitors on the skin. Scratching provides temporary relief by inflicting a little pain, which inhibits the sensation of itching. However, scratching further damages the skin and activates nerve fibers, intensifying the itch-scratch cycle. The neurotransmitter serotonin plays a role in this cycle, inhibiting pain but also activating itch neurons. Scratching also activates the brain's reward system, providing pleasure. While there are treatments available, efforts are being made to develop therapeutics that target neural pathways involved in itching. In the meantime, refraining from scratching can be challenging, but alternative methods like cold compresses or intense heat can help interrupt the sensation.