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Stem Cell Transplantation

All articles tagged with #stem cell transplantation

health1 month ago•11 min saved

Hybrid Immune Transplants Reverse Type 1 Diabetes in Mice

Stanford researchers show that in mice, a combined transplant of donor blood stem cells and mismatched pancreatic islet cells can restore insulin production and retrain the immune system, curing or preventing autoimmune Type 1 diabetes without immunosuppressants or graft-versus-host disease for at least six months, using CD117 antibody–based conditioning to create a hybrid immune system and a path toward human translation (with challenges like donor islet availability).

via SciTechDaily|

#graft-versus-host-disease #health #immune-system-reset

health4 months ago•2 min saved

Multiple Cases of HIV Remission Highlight Advances in Stem Cell Therapy

A study reports sustained HIV-1 remission in a patient following heterozygous CCR5Δ32 stem cell transplantation, highlighting a potential pathway for HIV cure research.

via Nature|

#berlin #ccr5d32 #health

health2 years ago•4 min saved

Stem cell transplantation: A pain-relieving solution for knee osteoarthritis

Stem cell transplantation, specifically using stem cells from umbilical tissue or a person's own adipose fat, has been found to be an effective and safe treatment for knee osteoarthritis pain and loss of function, according to a meta-analysis of 16 studies involving 875 patients. The analysis showed that all stem cell treatments resulted in a significant decrease in knee pain starting at three months of treatment. Knee osteoarthritis affects millions of people worldwide, and stem cell therapy offers promising potential for alleviating symptoms and improving joint function. However, further research is needed to standardize treatment protocols and evaluate long-term efficacy and safety.

via Medical News Today|

#health #knee-osteoarthritis #meta-analysis

health3 years ago•4 min saved

FDA approves Omisirge cell therapy to reduce infection risk in blood cancer patients.

The FDA has approved Omisirge, a cell therapy for patients with blood cancers who are planned for umbilical cord blood transplantation following a myeloablative conditioning regimen. The therapy quickens the recovery of neutrophils and reduces the risk of infection. Omisirge is composed of human allogeneic stem cells from umbilical cord blood that are processed and cultured with nicotinamide. The safety and effectiveness of Omisirge was supported by a randomized, multicenter study comparing transplantation of Omisirge to transplantation of umbilical cord blood.

via FDA.gov|

#blood-cancers #cell-therapy #fda