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Tormentil

All articles tagged with #tormentil

science1 month ago•4 min saved

Bogland tormentil: a wildflower unlocking new ways to fight resistant bacteria

Lab tests show tormentil root extracts from bogland inhibit growth of antibiotic‑resistant bacteria, reduce biofilm formation, and boost the effectiveness of the antibiotic colistin at low doses. The active compounds ellagic acid and agrimoniin appear to work by iron chelation, starving bacteria of a key nutrient and hindering growth, pointing to a potential plant‑derived route to new antimicrobials and combination therapies.

via SciTechDaily|

#antibiotic-resistance #antimicrobial #biofilms

plants1 month ago•20 min saved

Tormentil wildflower offers new angle against antibiotic-resistant superbugs

A Southampton-led study finds tormentil, a small yellow bogland wildflower, slows the growth of the drug-resistant bacterium Acinetobacter baumannii and may boost the effectiveness of the last-resort antibiotic colistin. The researchers identified two active compounds, agrimoniin and ellagic acid, that starve bacteria of iron, with consistent antimicrobial activity across three Irish bogs, suggesting potential for plant-based drug development—though translating these findings into safe, effective medicines will require extensive further work.

via Earth.com|

#acinetobacter-baumannii #antibiotic-resistance #antimicrobial-compounds

science1 month ago•5 min saved

Tiny Bog Wildflower Offers Hope Against Drug-Resistant Bacteria

New research on bogland plants from Ireland finds tormentil extracts inhibit bacteria and biofilm formation, and can enhance the effectiveness of the last-resort antibiotic colistin; compounds like ellagic acid and agrimoniin may work by iron chelation, pointing to plant-derived antimicrobials as a potential aid against drug-resistant infections, with further formulation work underway.

via ScienceAlert|

#antibiotic-synergy #antimicrobial-resistance #biofilms

health1 month ago•4 min saved

Wild tormentil uncovers plant compounds that fend off superbugs and boost antibiotics

A study screening bogland plants found tormentil (Potentilla erecta) extracts to be antimicrobial, to limit biofilm formation, and to enhance the effectiveness of the last-resort antibiotic colistin when used together, via compounds like ellagic acid and agrimoniin that appear to work by iron chelation; this highlights plant compounds as sources of new antimicrobials and antibiotic adjuvants amid rising antimicrobial resistance.

via The Conversation|

#antimicrobial-resistance #biofilms #combination-therapy