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Vaccine Design

All articles tagged with #vaccine design

AI-designed universal coronavirus vaccine shows safety and immune response in first human trial
technology1 month ago

AI-designed universal coronavirus vaccine shows safety and immune response in first human trial

Researchers from Cambridge and Southampton used AI to design a ‘super-antigen’ vaccine intended to protect against multiple Sarbeco coronaviruses. In a Phase I trial, the vaccine was safe and elicited immune responses in 39 healthy volunteers when delivered via a needle-free micro-fluid jet, suggesting a potential future-proof solution against current and emerging coronaviruses, though larger and more diverse trials are needed and concerns about AI in medicine remain.

Harnessing AI to Predict and Prepare for Future Pandemics
science-and-technology2 years ago

Harnessing AI to Predict and Prepare for Future Pandemics

Researchers are harnessing the power of artificial intelligence (AI) tools, such as AlphaFold and large language models, to prepare for future pandemics. These AI tools are being used to map the structure of viral proteins, identify mutations for vaccine development, predict virus evolution, and design new proteins for vaccine candidates. The use of AI in pandemic preparedness has shown promising results, but it is still in the early stages. Machine learning has the potential to accelerate vaccine design and stay ahead of evolving viruses, but caution is needed in relying solely on computational design.