Hidden gut sugars linked to ALS and dementia, opening new therapy paths
TL;DR
New research shows harmful sugars produced by gut bacteria trigger immune responses that damage brain cells in ALS and frontotemporal dementia; elevated levels were found in a majority of patients studied, and experiments reducing these sugars improved brain health and lifespan, pointing to gut-targeted therapies and biomarkers to slow disease progression—especially in carriers of the C9orf72 mutation.
Topics:healthhealth-and-medicine#als#frontotemporal-dementia#glycogen#gut-microbiome#health-and-medicine#neuroinflammation
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