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Als

All articles tagged with #als

Hidden gut sugars linked to ALS and dementia, opening new therapy paths
health-and-medicine2 days ago

Hidden gut sugars linked to ALS and dementia, opening new therapy paths

New research shows harmful sugars produced by gut bacteria trigger immune responses that damage brain cells in ALS and frontotemporal dementia; elevated levels were found in a majority of patients studied, and experiments reducing these sugars improved brain health and lifespan, pointing to gut-targeted therapies and biomarkers to slow disease progression—especially in carriers of the C9orf72 mutation.

Ross The Boss Friedman, Manowar’s founding guitarist, dies at 72
music14 days ago

Ross The Boss Friedman, Manowar’s founding guitarist, dies at 72

Ross 'The Boss' Friedman, the pioneering guitarist and founding member of The Dictators and Manowar, has died at 72. His passing was confirmed by the Metal Hall of Fame days after he was diagnosed with ALS, with a fundraising drive recently launched to help cover his medical care. Friedman’s work bridged punk and metal, influencing generations of musicians with his fearless style and machine‑like guitar tone, leaving a lasting legacy in heavy metal history.

New Gut-Brain Link Points to ALS/FTD Treatments
science24 days ago

New Gut-Brain Link Points to ALS/FTD Treatments

Case Western Reserve University researchers report a gut-brain connection in ALS and frontotemporal dementia (FTD): harmful gut bacteria may produce inflammatory glycogen-like sugars that trigger immune responses damaging brain cells. In a study of 23 ALS/FTD patients, about 70% had high levels of these sugars versus roughly 33% of controls, suggesting gut microbes could act as an environmental trigger, especially in C9orf72 mutation carriers. The work identifies potential biomarkers and gut-targeted therapies, including degrading the sugars and modulating gut-brain signaling, with germ-free mouse models and a novel sterile housing system enabling larger-scale studies; preliminary results hint that reducing these sugars could improve brain health and may lead to clinical trials within a year.

TDP43's DNA repair role links ALS to dementia and cancer risk
health-and-medicine27 days ago

TDP43's DNA repair role links ALS to dementia and cancer risk

Researchers find that the ALS-linked protein TDP43 regulates DNA mismatch repair; when its levels are imbalanced, repair genes overactivate, damaging neurons and destabilizing the genome, and higher TDP43 amounts correlate with more tumor mutations, placing this protein at a crossroads of neurodegeneration and cancer with potential therapeutic implications.

Final Voice Forward: Rebecca Gayheart Dane Promotes AI-Powered Voice Restoration for ALS
technology1 month ago

Final Voice Forward: Rebecca Gayheart Dane Promotes AI-Powered Voice Restoration for ALS

Rebecca Gayheart Dane discusses her husband Eric Dane’s battle with ALS and his involvement in ElevenLabs’ AI voice restoration project, which used past recordings to recreate a lifelike voice for communication. The initiative, including the ‘11 Voices’ docu-shorts and a pledge of lifetime licenses and support, aims to help up to a million people with voice loss, with Dane’s legacy and SXSW premiere fueling advocacy for the technology and its ethical use.

Eric Dane's Death Officially Attributed to ALS-Linked Respiratory Failure
entertainment1 month ago

Eric Dane's Death Officially Attributed to ALS-Linked Respiratory Failure

Eric Dane, best known for Grey's Anatomy, died at 53 and, according to the Los Angeles County Medical Examiner, his official cause of death was respiratory failure linked to amyotrophic lateral sclerosis (ALS). Dane had publicly disclosed his ALS diagnosis last year, and his passing prompted an outpouring of tributes from co-stars and friends across the entertainment industry.

Eric Dane Dies at 53: ALS-Linked Respiratory Failure Confirmed
entertainment1 month ago

Eric Dane Dies at 53: ALS-Linked Respiratory Failure Confirmed

Eric Dane died at age 53 on Feb. 19 from respiratory failure, with ALS listed as an underlying cause on the death certificate. The actor had publicly disclosed his ALS diagnosis in 2025 and used his platform to advocate for awareness and research; he spent his final days with wife Rebecca Gayheart and his daughters Billie and Georgia, with the family asking for privacy.

Eric Dane’s ALS battle ends: cause of death confirmed at 53
entertainment1 month ago

Eric Dane’s ALS battle ends: cause of death confirmed at 53

Eric Dane died at 53; officials confirmed the Feb. 19 death was due to amyotrophic lateral sclerosis (ALS), with respiratory failure listed as the immediate cause on his death certificate. Diagnosed with ALS in April 2025, Dane advocated for awareness and research during his illness. He is survived by wife Rebecca Gayheart and their two daughters, Billie Beatrice and Georgia Geraldine; known for Grey’s Anatomy and Euphoria, among other roles.

Eric Dane Dies After ALS-Linked Respiratory Failure
obituaries1 month ago

Eric Dane Dies After ALS-Linked Respiratory Failure

Eric Dane died on Feb. 19 from respiratory failure, with ALS listed as a contributing cause on his death certificate, per People. His family said he spent his final days surrounded by loved ones and highlighted his ALS advocacy after revealing his diagnosis last year. The Grey’s Anatomy and Euphoria star was 53 at the time of his passing and will be remembered for his film and TV work as well as his advocacy.

Eric Dane dies at 53 from respiratory failure linked to ALS, death certificate reveals
entertainment1 month ago

Eric Dane dies at 53 from respiratory failure linked to ALS, death certificate reveals

Eric Dane, best known for Grey's Anatomy, died Feb. 19 in Los Angeles after a days-long battle with ALS. A death certificate obtained by USA TODAY lists respiratory failure as the immediate cause and ALS (Lou Gehrig’s disease) as the underlying condition. Dane had publicly disclosed his ALS diagnosis in 2025 and had become an advocate for awareness and research; he is survived by his wife Rebecca Gayheart and their two daughters.