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Atlas of brain microproteins offers new angles on Alzheimer’s

1 min read
Source: Nature
Atlas of brain microproteins offers new angles on Alzheimer’s
Photo: Nature
TL;DR

A Nature Aging study mapped more than 4,300 brain microproteins in post-mortem dorsolateral prefrontal cortex samples, validating 1,067 with high confidence through deep learning; 3,217 microproteins were previously uncharacterized. Several microproteins show altered expression in Alzheimer's, creating a comprehensive atlas that could reveal new aging and neurodegeneration mechanisms and guide future validation.

Topics:healthscience#aging#alzheimers#brain#microproteins#proteomics#science
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  1. Map of brain ‘microproteins’ could offer new clues to Alzheimer’s disease  Nature
  2. A microprotein atlas of the human frontal cortex in Alzheimer’s disease  Nature
  3. Microproteins provide new playbook for Alzheimer's research  Medical Xpress
  4. A microglial cell within which an uncharacterized microprotein accumulates around its nucleus  EurekAlert!
  5. New brain atlas can aid fight against Alzheimer’s disease  ThePrint

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