Coffee's Hidden Helpers: Regular and Decaf Brew Shape Your Gut and Mood

A Nature Communications study from APC Microbiome Ireland finds regular coffee consumption reshapes the gut microbiome, lowers inflammatory markers, and improves mood, with both caffeinated and decaffeinated coffee exerting distinct, caffeine-independent effects; a two-week abstinence altered some responses and reintroduction produced rapid microbiome changes, highlighting coffee’s complex mix of bioactive compounds that influence the gut-brain axis as part of a balanced diet.